ArticleNature. Mental health2025
Cross-Sectional Mega-Analysis of Resting-State Alterations Associated with Autism and Attention-Deficit/Hyperactivity Disorder in Children and Adolescents.
Article in Nature. Mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A resting-state functional magnetic resonance imaging meta-analysis of differences in brain activity between children and adolescents with attention-deficit/hyperactivity disorder using activation likelihood estimation.European child & adolescent psychiatry · 2026Pooled it
- Aberrant multivariate mapping between behavioral profiles and cortical morphological brain networks in children with autism spectrum disorder.Translational psychiatry · 2026Article
- Developmental trajectories of glutamate and the variable clinical course of ADHD in youth.Translational psychiatry · 2026Article
- Optimizing functional connectivity scanning conditions for predicting autistic traits.medRxiv : the preprint server for health sciences · 2026Article
- Optimizing functional connectivity scanning conditions for predicting autistic traits.Nature. Mental health · 2026Article
- The Developmental Approach to Autism Science: Considering Cognitive Ability in the Age of Neuroimaging Research.Developmental psychobiology · 2026Review
- Midbrain hypoactivation and mesocortical hypoconnectivity in inhibitory control learning in autism.Brain communications · 2026Article
- Overlap and Differences of Autism and ADHD: Digital Phenotyping of Movement and Communication During Development.bioRxiv : the preprint server for biology · 2025Article
- Neurofeedback for ADHD: Exploring the Role of Quantitative EEG and Brainwave Modulation.Brain and behavior · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Autism Spectrum Disorder (autism) and Attention Deficit/Hyperactivity Disorder (ADHD) often co-occur, although it remains unclear if these conditions share common neurobiological foundations or exhibit distinct alterations in resting-state brain connectivity. We conducted a cross-sectional mega-analytic comparison of functional connectivity patterns linked to autism and ADHD traits in children and adolescents (ages 6-19 years; n=10,168), with follow-up analyses considering autism (n=764 autistic; n=893 neurotypical) and ADHD diagnoses (n=2,026 ADHD; n=2,409 neurotypical). In total, 12,732 unique child and adolescent participants were included: 3,528 in both analyses, 6,640 in the trait analysis only, and 2,564 in the diagnostic analysis only. Autism traits and diagnosis were associated with reduced connectivity between the thalamus, putamen, salience/ventral attention, and frontoparietal networks, while ADHD traits showed the opposite pattern. Hyperconnectivity between the default mode and dorsal attention networks was observed in both autistic and ADHD groups relative to neurotypical individuals and associated with ADHD traits. Despite frequent co-occurrence, autism and ADHD traits exhibit distinct neural signatures, with small effect sizes indicating subtle associations.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.