Analysis of Reddit Reveals Clascoterone Questions Among People with Acne.

Jennifer Wang, Paras Patel, Jessica Mineroff, Jared Jagdeo

Abstract read

In one paragraph

Article in The Journal of clinical and aesthetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jennifer WangDr. Wang, Dr. Mineroff, and Dr. Jagdeo are with the Department of Dermatology at State University of New York, Downstate Health Sciences University in Brooklyn, New York and the Dermatology Service at the Veterans Affairs New York Harbor Healthcare System - Brooklyn Campus in Brooklyn, New York.

Paras PatelDr. Patel is with the Rowan University School of Osteopathic Medicine in Stratford, New Jersey and the Dermatology Service at the Veterans Affairs New York Harbor Healthcare System - Brooklyn Campus in Brooklyn, New York.

Jessica MineroffDr. Wang, Dr. Mineroff, and Dr. Jagdeo are with the Department of Dermatology at State University of New York, Downstate Health Sciences University in Brooklyn, New York and the Dermatology Service at the Veterans Affairs New York Harbor Healthcare System - Brooklyn Campus in Brooklyn, New York.

Jared JagdeoDr. Wang, Dr. Mineroff, and Dr. Jagdeo are with the Department of Dermatology at State University of New York, Downstate Health Sciences University in Brooklyn, New York and the Dermatology Service at the Veterans Affairs New York Harbor Healthcare System - Brooklyn Campus in Brooklyn, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatients with acne are increasingly using social media platforms such as Reddit to seek medical information. Skincare subreddits such as r/SkinCareAddiction, r/Skincare_Addiction, r/SkincareAddicts, and r/Acne have become important hubs of discussion for acne treatments, including the recently US Food and Drug Administration (FDA)-approved drug clascoterone (Winlevi). The objective of this study was to analyze questions and information needs of Reddit users with acne related to clascoterone.

methodsThe authors analyzed all clascoterone-related questions posted on the r/SkinCareAddiction, r/Skincare_Addiction, r/SkincareAddicts, and r/Acne subreddits. Questions were categorized and subcategorized for analysis.

resultsA total of 301 questions from 223 posts were analyzed. The largest proportion of questions were about concurrent use with other medical interventions or skincare regimens (25.9%) and adverse effects (17.3%). General experiences (14.0%) and usage instructions (12.0%) also made up a significant number of questions. LIMITATIONS: A limitation of this study is that Reddit users may not accurately represent the general population of patients with acne using clascoterone.

conclusionThis Reddit analysis of clascoterone therapy reveals key themes in questions and gaps in knowledge among people with acne that may not be readily apparent in clinical settings. This information can guide physicians to better address patient needs and improve patient outcomes.

Indexed as

AcneclascoteroneRedditsocial mediaWinlevi

Identifiers

PMID41446720

PMCPMC12724977

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.