Evidence map›Paper›PMID 41446631›Full record

ArticleFrontiers in endocrinology2025

Serum luteinizing hormone trajectories during ovarian stimulation and their outcomes of IVF/ICSI: a retrospective cohort study.

Conghui Liu, Jiawei Wang, Jing Tian, Shengyuan Chen, Wei Bao, Lei Luo, Limin Wu, Ye Meng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Conghui LiuCenter for Reproduction and Genetics, Department of Gynecology and Obstetrics, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Jiawei WangCenter for Reproduction and Genetics, Department of Gynecology and Obstetrics, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Jing TianMenzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.
Shengyuan ChenCenter for Reproduction and Genetics, Department of Gynecology and Obstetrics, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Wei BaoInstitute of Public Health Sciences, Division of Life Sciences Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Lei LuoCenter for Reproduction and Genetics, Department of Gynecology and Obstetrics, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Limin WuCenter for Reproduction and Genetics, Department of Gynecology and Obstetrics, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Ye MengCenter for Reproduction and Genetics, Department of Gynecology and Obstetrics, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: An appropriate luteinizing hormone (LH) level during ovulation stimulation (OS) is important for positive Methods: This study was a retrospective cohort study that included 2,716 patients who underwent GnRH-ant protocol for OS from 1 January 2017 to 31 June 2024. Multiple serum LH measurements during OS were collected. Group-based trajectory modeling was used to identify subgroups of participants who shared similar LH trajectories. Patients' characteristics and IVF/ICSI outcomes across the identified LH trajectories were compared. Furthermore, linear and log-binomial regression models were used to assess the association of LH trajectories with IVF/ICSI and pregnancy outcomes. Results: Three discrete LH trajectories were identified: persistently low (90.7%, Conclusions: Patients with an elevated number of AFC and basal LH were more likely to exhibit unstable LH trajectories. Higher LH trajectories during ovarian stimulation were associated with a better quantity rather than the quality of oocytes or embryos.

Indexed as

Fertilization in VitroLuteinizing HormoneOvulation InductionSperm Injections, IntracytoplasmicAdultFemaleGonadotropin-Releasing HormoneHumansPregnancyPregnancy OutcomePregnancy RateRetrospective StudiesGonadotropin-Releasing HormoneLuteinizing HormoneGnRH antagonistsIVF/ICSIluteinizing hormone (LH)ovarian stimulation (OS)trajectories

Identifiers

PMID41446631
PMCPMC12722849

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.