Evidence map›Paper›PMID 41446571›Full record

ArticleFrontiers in environmental science2025

Occurrence of enterotoxigenic

Fatema-Tuz Johura, Marzia Sultana, Jade Lewis, Abdus Sadique, David A Sack, Richard B Sack, Munirul Alam, Subhra Chakraborty

Abstract read
In one paragraph

Article in Frontiers in environmental science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fatema-Tuz JohuraDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Marzia SultanaInfectious Diseases Division, icddr,b Formerly Known as International Center for Diarrheal Disease Research, Dhaka, Bangladesh.
Jade LewisDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Abdus SadiqueInfectious Diseases Division, icddr,b Formerly Known as International Center for Diarrheal Disease Research, Dhaka, Bangladesh.
David A SackDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Richard B SackDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Munirul AlamInfectious Diseases Division, icddr,b Formerly Known as International Center for Diarrheal Disease Research, Dhaka, Bangladesh.
Subhra ChakrabortyDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.

Funding

EPIDEMIOLOGY &ECOLOGY OF VIBRIO CHOLERAE IN BANGLADESHR01AI039129 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SACK, DAVID A · 1996 to 2014
$15.2M
Maternally acquired immunity in protection against enterotoxigenic E. coli infections in infantsR56AI168316 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CHAKRABORTY, SUBHRA, GILMAN, ROBERT H · 2024 to 2024
$571k
NIAID NIH HHS R01 AI039129NIAID NIH HHS R56 AI168316
6 · The paper itself

Abstract

Background: The prevalence of ETEC in the environment could be influenced by environmental factors, which may contribute to seasonal outbreaks. This study assessed the seasonal prevalence of the ETEC population in water bodies in relation to ecological changes in Bangladesh. Method: The presence of ETEC in water, plankton, and sediment samples collected from water bodies in Mathbaria, a southern coastal region, was investigated using quantitative PCR (qPCR) and an extensive culture method over a year. Concurrently, the physico-chemical parameters of the water were measured. We also tested aquatic samples from Chhatak, a northern hilly region. Results: ETEC was detected in a high proportion (56%-78%) in water, plankton, and sediment samples from both sites. In Mathbaria, higher abundance of ETEC was noted in fall and spring, followed by summer and lowest in the monsoon. ETEC positivity was high in winter by qPCR, but no viable ETEC could be isolated. Environmental conditions such as neutral to low alkaline pH, elevated dissolved oxygen levels, and warmer water temperatures showed a trend of association with increased ETEC prevalence. Conclusion: The persistence of ETEC in environmental water and their association with ecologic factors may help to explain seasonal illnesses in people.

Indexed as

Bangladeshclimateecological parametersenterotoxigenic E. colienvironment

Identifiers

PMID41446571
PMCPMC12724539

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.