ArticleFrontiers in public health2025
Assessing awareness of latent tuberculosis infection: the urgent need for clinical governance-driven education in rural Eastern Cape - insights from a community-based study.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Latent tuberculosis infection (LTBI) affects approximately a quarter of the global population and poses a significant barrier to TB control, particularly in high-burden settings like South Africa. Public awareness of LTBI remains limited, with widespread misconceptions, especially within rural healthcare systems. This study assessed community knowledge of LTBI, evaluated the impact of prior educational exposure, and identified sociodemographic disparities and stigma-related beliefs in a rural Eastern Cape community. Methods: A cross-sectional study was conducted using a convenience sampling strategy among 245 adults attending a rural primary care facility in a high TB-burden area. A structured questionnaire was administered to assess participants' knowledge of LTBI, including its differentiation from active TB, associated risk factors, and treatment options. Results: Among participants (62% female, 99.6% Black African), LTBI knowledge was significantly higher among those with prior educational exposure (77% vs. 46%, Conclusion: Structured LTBI education substantially improves community knowledge. However, interventions must be tailored to demographic and cultural contexts to address stigma and misconceptions effectively. Integrating LTBI education into clinical governance and quality assurance frameworks may promote equitable, consistent, and stigma-sensitive TB prevention in rural settings, thereby contributing to improved patient outcomes and a stronger health system.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.