ReviewCureus2025
Impact of Sleep Apnea Treatment With Continuous Positive Airway Pressure (CPAP) on Blood Pressure Control in Resistant Hypertension: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-risk cardiovascular factors such as resistant hypertension (RH) are often correlated with obstructive sleep apnoea (OSA), which can further contribute to the elevation of blood pressure (BP) and cardiovascular morbidity. The use of continuous positive airway pressure (CPAP) therapy has been suggested to be an effective intervention to enhance the management of BP in patients with RH and OSA. The purpose of this systematic review and meta-analysis was to determine the impact of CPAP treatment on the decrease in BP and associated heart parameters in this risk group. Randomised controlled trials (RCTs), prospective intervention studies, and observational studies published between 2010 and 2025 were searched in PubMed, Cochrane Library, and Google Scholar using a comprehensive literature search. A random-effects model was performed: the pooled effect sizes showed that CPAP therapy had a significantly lower BP than the control (r = 0.96, 95% CI: 0.64-1.28), which is a moderate effect size. Subgroup analysis indicated that the longer the period and the higher the BP reductions were, the greater the adherence. There was high heterogeneity (I² = 92.72%), which was associated with variations in study populations, CPAP compliance, and intervention protocols. None of the publication bias was significant. Finally, CPAP treatment is a beneficial adjunctive treatment to enhance BP control in RH and OSA patients and has other cardiovascular advantages. Adherence to therapies is more beneficial in the long term, which explains the need to tailor treatment plans to individual needs. Long-term cardiovascular outcomes, the optimisation of adherence, and predictors of response to CPAP therapy in this population should be addressed in future research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.