ArticleThe breast journal2025
Fear of Cancer Recurrence Contributes Largely to Patient Anxiety and Depression and Quality of Life in a Prospective Cohort of Chinese Breast Cancer Patients for Postoperative Radiotherapy.
Article in The breast journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Cancer Survivorship After COVID-19: Psychological Burden, Symptom Experience, and Social Support.Medicina (Kaunas, Lithuania) · 2026Article
- Insomnia in Breast Cancer: A Neglected Symptom Cluster.Journal of clinical medicine · 2026Review
- Factors Influencing Fear of Progression in Endometriosis: A Path Analysis Using the Common-Sense Model.Journal of multidisciplinary healthcare · 2026Article
- Fear of Cancer Recurrence Contributes Largely to Patient Anxiety and Depression and Quality of Life in a Prospective Cohort of Chinese Breast Cancer Patients for Postoperative Radiotherapy.The breast journal · 2025Article
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Authors and funding
10 authors.
Funding
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Abstract
Background: Fear of cancer recurrence (FCR) is common among Chinese breast cancer (BC) patients following surgery, chemotherapy, and radiotherapy (RT). Understanding the prevalence and impact of FCR, particularly during the RT period, on anxiety, depression, and quality of life may inform strategies to manage patient distress. Methods: From July 2015 to December 2016, 486 women undergoing RT for BC at the Fourth Hospital of Hebei Medical University, China, were prospectively enrolled in the study. Anxiety, depression, and quality-of-life changes were assessed using the Hospital Anxiety and Depression Scale (HADS) and the European Organization for Research and Treatment of Cancer's Quality-of-Life questionnaires (QLQ-C30, QLQ-BR23) before and after RT. FCR was assessed using a modified question from the QLQ-BR23, Results: Of the 486 women enrolled, 23 (4.7%) patients declined participation. Of the 463 analyzed patients, the mean age was 47 years old. 386 patients (83.4%) elected for mastectomies. FCR levels prior to RT were reported as " Conclusions: FCR is a significant contributor to psychological distress and reduced quality of life among Chinese breast cancer patients during the RT period. Routine screening for anxiety and depression and targeted intervention for FCR should be prioritized in this population.
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