ArticleOncoscience2025
Necrotizing fasciitis of the head and neck - clinical features, diagnostics, and management strategies.
Article in Oncoscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Recognizing Descending Necrotizing Mediastinitis in Adults: A Narrative Review of Diagnostic Dilemmas and Barriers.Cureus · 2026Review
- Fatal Emphysematous Tonsillopharyngitis With Laryngocele Involvement Revealing Acute Myeloid Leukemia M5 Subtype: A Previously Undescribed Presentation.Case reports in oncological medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNecrotizing fasciitis (NF) of the head and neck is a rare but rapidly progressive and life-threatening soft tissue infection that constitutes a true surgical emergency. Due to the complex anatomy of the cervicofacial region and the proximity to the upper airway, early diagnosis and management are particularly challenging, and delayed recognition is associated with high morbidity and mortality. This article aims to provide a concise and clinically oriented overview of the presentation, diagnostic pitfalls, and current management strategies for cervicofacial necrotizing fasciitis.
methodsA narrative review of the available literature was conducted and complemented by clinical experience from a tertiary referral center. Key aspects including etiology, risk factors, clinical features, imaging findings, laboratory parameters, microbiology, surgical management, airway control, and adjunctive therapies were synthesized and critically discussed.
resultsCervicofacial NF often presents with disproportionate pain, rapidly progressive swelling, and early systemic toxicity. Odontogenic infections represent the most common source, frequently in the presence of systemic comorbidities such as diabetes mellitus or immunosuppression. Contrast-enhanced computed tomography is the imaging modality of choice, whereas laboratory scoring systems such as the LRINEC score show limited sensitivity in head and neck infections. The cornerstone of treatment is immediate and aggressive surgical debridement combined with broad-spectrum intravenous antibiotics, early airway protection, and intensive care support. Repeated surgical interventions are frequently required. The role of adjunctive hyperbaric oxygen therapy remains controversial and cannot be routinely recommended based on current evidence.
conclusionNecrotizing fasciitis of the head and neck requires a high index of suspicion, prompt imaging, and decisive multidisciplinary management. Early surgical intervention and airway control are critical determinants of outcome. Given the rarity of cervicofacial NF, further multicenter studies and registries are needed to refine diagnostic tools, identify prognostic factors, and optimize treatment strategies, particularly in high-risk populations such as immunocompromised and oncologic patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.