Evidence map›Paper›PMID 41446316›Full record

ReviewJournal of hand surgery global online2026

Radiation-Induced Brachial Plexopathy: Current Understanding, Diagnosis, and Treatment Options.

Alex G Lambi, Tomas Holy, Ryan E Tomlinson, Mary F Barbe

Abstract readReview
In one paragraph

Review in Journal of hand surgery global online, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alex G LambiDepartment of Surgery Division of Plastic Surgery, University of New Mexico School of Medicine, Albuquerque, NM.
Tomas HolyDepartment of Orthopedics and Rehabilitation, University of New Mexico School of Medicine, Albuquerque, NM.
Ryan E TomlinsonDepartment of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA.
Mary F BarbeAging and Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.

Funding

Biomarkers of Tissue Tolerance and Behavior in a Rat ModelR01AR056019 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI BARBE, MARY F · 2009 to 2025
$7.3M
NGF-TrkA Signaling in Load-Induced Bone FormationR01AR074953 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI TOMLINSON, RYAN · 2019 to 2023
$1.7M
NIAMS NIH HHS R01 AR056019NIAMS NIH HHS R01 AR074953
6 · The paper itself

Abstract

Radiation-induced brachial plexopathy (RIBP) is a gruesome complication of cancers treated with radiation therapy around the lung and chest wall, head and neck, and breast and axilla. It can occur in an early-onset (transient) or a late-onset (chronic) fashion. The diagnosis involves exclusion of a compressive neoplastic process, either new or recurrent, and relies largely on patient symptomatology without well-validated, objective scoring systems. Treatment options remain limited as no major advances have been made to prevent or halt disease progression. This article reviews the background incidence, pathophysiology, and diagnosis of RIBP. In addition to surgical treatment options, nonsurgical modalities, often the mainstay of symptom management, are discussed. Lastly, the current challenges in treating RIBP are highlighted with an emphasis on targeting the underlying culprit-radiation-induced fibrosis.

Indexed as

Brachial plexusFibrosisPlexopathyRadiotherapyRIBP

Identifiers

PMID41446316
PMCPMC12723156

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.