ArticleJournal of hand surgery global online2026
Carpal Tunnel Release Postoperative Pain Management: A Systematic Review of Randomized Controlled Trials.
Article in Journal of hand surgery global online, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The management of postoperative pain after carpal tunnel release (CTR) has evolved over the years. This article reviews various approaches to pain management in the literature. Methods: An electronic search was conducted using PubMed, Google Scholar, and SCOPUS for studies on CTR pain management using either preoperative, perioperative, or postoperative tools. Only randomized controlled trials were included in the narrative review. Articles included in the study evaluated patients diagnosed with carpal tunnel syndrome, underwent CTR, and had preoperative, perioperative, or postoperative intervention evaluated as a primary end point. Duration and quantity of opioids, and patient-reported pain scales, such as the visual analog scale, were calculated and compared. Results: During the study period between 2015 and 2022, 10 randomized controlled trials met the inclusion criteria. Of these, studies were analyzed as either preoperative, perioperative, or postoperative means of managing pain. When these techniques were compared with opioid usage, no notable differences were found in pain ratings between patients who were given opioids for pain management compared with those provided with these nonopioid pain management options. Conclusions: This review highlights the effectiveness of various preoperative, perioperative, and postoperative interventions for pain management after CTR. Although opioids are the current standard for pain management after CTR, our study highlights interventions that are as effective, if not more so, as opioids at lowering pain scores with this procedure. Clinical relevance: The success of the studied alternatives in reducing pain outcomes for CTR can help mitigate the number of opioids prescribed to patients for the procedure. Given the current opioid epidemic plaguing the nation, understanding the efficacy of all other nonaddictive alternatives for pain management with CTR is imperative.
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