Evidence map›Paper›PMID 41446231›Full record

ArticlebioRxiv : the preprint server for biology2025

Rotational settings quantize nucleosome movement by chromatin regulators.

Van La, Abby Trouth, Vijay Ramani, Srinivas Ramachandran

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Van LaStructural Biology, Biochemistry, and Biophysics Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Abby TrouthStructural Biology, Biochemistry, and Biophysics Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0001-6563-2277
Vijay RamaniDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0003-3345-5960
Srinivas RamachandranDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0003-2929-1377

Funding

Maintenance of cellular memory during replicationR35GM156411 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI Srinivas Ramachandran · 2025 to 2026
$855k
NIGMS NIH HHS R35 GM156411
6 · The paper itself

Abstract

Proper nucleosome positioning is essential for gene regulation and genomic integrity. Regulated nucleosome assembly and positioning results from a need to protect DNA sequences genome-wide, constrained by the known intrinsic sequence preferences of histones. Current models posit that chromatin regulators override the intrinsic preferences to establish the nucleosome landscapes observed

Indexed as

10 bp quantized shiftshigh-resolution mappingRotational positioning

Identifiers

PMID41446231
PMCPMC12724613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.