Evidence map›Paper›PMID 41446223›Full record

ArticlebioRxiv : the preprint server for biology2025

A Multi-Modal Transfer Learning Framework to Reduce Health Disparities in Prostate Adenocarcinoma.

Lusheng Li, Jieqiong Wang, Shibiao Wan

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lusheng LiDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, USA.
Jieqiong WangDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA.
Shibiao WanDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, USA.ORCID 0000-0003-0661-2684

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Apar Kishor Ganti · 1985 to 2026
$55.0M
Leveraging Heterogenous Common Fund Data Sets and Beyond for Identifying Lung Cancer SubtypesR03OD038391 · OD · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WAN, SHIBIAO, WANG, JIEQIONG · 2024 to 2024
$307k
NCI NIH HHS P30 CA036727NIGMS NIH HHS P20 GM103427NIH HHS R03 OD038391
6 · The paper itself

Abstract

Prostate cancer is the second most common cancer in men across the United States, of which prostate adenocarcinoma (PRAD) is the most common subtype. Despite remarkable progress has been made in PRAD diagnosis and prognosis, Black American men have been found to have disproportionately high incidence and mortality rate in PRAD compared with non-Hispanic White men in the United States. While machine learning (ML) methods like transfer learning (TL) have shown promise in reducing racial disparities in PRAD, its effectiveness is often compromised by the requirement for large-scale training datasets, which are challenging to obtain in clinical settings. In addition, existing ML approaches only leverage single-omics data without integrating multi-omics information. To address these concerns, we propose a novel approach called

Identifiers

PMID41446223
PMCPMC12724439

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.