Evidence map›Paper›PMID 41446159›Full record

ArticlebioRxiv : the preprint server for biology2025

Verbal versus Nonverbal Processing Leads to Generalized Hemispheric Laterality Effects that Span Multiple Networks.

Wendy Sun, Lauren M DiNicola, Randy L Buckner

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wendy SunDiv. of Medical Sciences, Harvard Medical School, Boston, MA.ORCID 0000-0001-7350-964X
Lauren M DiNicolaDept. of Psychology, University of Virginia, Charlottesville, VA.ORCID 0000-0001-7562-0755
Randy L BucknerDept. of Psychology, Center for Brain Science, Harvard University, Cambridge, MA.ORCID 0000-0001-6422-8037

Funding

Training in the Molecular Biology of Neurodegeneration and Alzheimer's DiseaseT32AG000222 · NIA · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Bruce A YANKNER · 1992 to 2026
$18.5M
Precision Mapping the Human Cerebellum for Neuromodulation and Understanding of Brain DisordersR01MH124004 · NIMH · HARVARD UNIVERSITY · PI BUCKNER, RANDY L, POLIMENI, JONATHAN RIZZO · 2020 to 2022
$1.8M
Upgrade Siemens MAGNETOM Trio to MAGNETOM Prisma Fit 3T Human MRI SystemS10OD020039 · OD · HARVARD UNIVERSITY · PI BUCKNER, RANDY L · 2015 to 2015
$600k
NIA NIH HHS T32 AG000222NIH HHS S10 OD020039NIMH NIH HHS R01 MH124004
6 · The paper itself

Abstract

Precision neuroimaging was used to explore specialization for verbal versus nonverbal processing. Consistent with prior findings, individuals exhibited a spatially left-lateralized association language network, with regions in both hemispheres robustly responding to processing of meaning-based sentences. We next examined differential responses to verbal (words) versus nonverbal (faces) materials within the same working memory task. The right hemisphere components of the language network responded more strongly to nonverbal than to verbal materials, splitting the network's functional profile between the hemispheres. Similar patterns were observed across multiple association networks including putative cognitive-control, action-mode, and attention networks. The hemispheric laterality effect was prospectively replicated in a second independent study. These findings highlight a generalized laterality phenomenon that transcends individual specialized networks and aligns with a broad mechanism that modulates processing between the hemispheres.

Identifiers

PMID41446159
PMCPMC12724449

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.