Evidence map›Paper›PMID 41446151›Full record

ArticlebioRxiv : the preprint server for biology2025

Structural Basis of TACO1-Mediated Efficient Mitochondrial Translation.

Shuhui Wang, Michele Brischigliaro, Yuekang Zhang, Chunxiang Wu, Wei Zheng, Antoni Barrientos, Yong Xiong

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Shuhui WangDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.ORCID 0000-0002-2393-9518
Michele BrischigliaroDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Yuekang ZhangDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
Chunxiang WuDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
Wei ZhengDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
Antoni BarrientosDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0001-9018-3231
Yong XiongDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.

Funding

Mitochondrial Biogenesis in Health and DiseaseR35GM118141 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BARRIENTOS, ANTONI · 2016 to 2025
$8.9M
NIGMS NIH HHS R35 GM118141
6 · The paper itself

Abstract

Translation elongation is a universally conserved step in protein synthesis, relying on elongation factors that engage the ribosomal L7/L12 stalk to mediate aminoacyl-tRNA delivery, accommodation, and ribosomal translocation. Using

Identifiers

PMID41446151
PMCPMC12724405

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.