Evidence map›Paper›PMID 41446104›Full record

ArticlebioRxiv : the preprint server for biology2025

Evaluation of the safety and insecticidal efficacy of ivermectin-treated bird feed formulations in different avian species.

Michelle J Savran, Kathryn Coffin, Claire M Stewart, Chilinh Nguyen, Catalina Puska, Molly E Ring, Anna-Sophia Leon, Preston Schweiner, Tilman Peters, Jenna C Randall and 7 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Michelle J SavranCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0002-4124-8622
Kathryn CoffinCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Claire M StewartCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Chilinh NguyenCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Catalina PuskaCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Molly E RingCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0009-0007-2719-430X
Anna-Sophia LeonCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Preston SchweinerCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0009-0009-9303-6232
Tilman PetersCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Jenna C RandallCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Jenny BuczekDepartment of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.ORCID 0009-0003-4032-4384
Paula LadoCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0003-4852-3495
Emily GallichotteCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0002-8937-5583
Brady ClapsaddleTDA Research Inc., Wheat Ridge, Colorado, USA.ORCID 0000-0002-9270-8713
Christopher M BarkerUniversity of California, Davis, Department of Pathology, Microbiology & Immunology, Davis, California, USA.ORCID 0000-0002-7941-346X
Gregory D EbelCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0002-4458-9959
Brian D FoyCenter for Vector-borne and Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0002-9117-203X

Funding

West Nile virus control through mosquitocidal avian bloodmealsR01AI148633 · NIAID · COLORADO STATE UNIVERSITY · PI FOY, BRIAN DAVID · 2020 to 2024
$3.3M
CSU Infectious Disease Research and Response Training ProgramT32AI162691 · NIAID · COLORADO STATE UNIVERSITY · PI DEAN, GREGG A · 2021 to 2025
$2.1M
Dual-Degree Medical Scientist Training Program for VeterinariansT32GM136628 · NIGMS · COLORADO STATE UNIVERSITY · PI ANNE C AVERY, Daniel Patrick Regan · 2020 to 2026
$1.9M
NIAID NIH HHS R01 AI148633NIAID NIH HHS T32 AI162691NIGMS NIH HHS T32 GM136628
6 · The paper itself

Abstract

Background: West Nile virus (WNV) is maintained in an enzootic cycle between reservoir host birds and Methods: Mosquitoes were collected during peak WNV transmission season in Northern Colorado and DNA extracted from blood meals to determine host species. Chickens, pigeons, zebra finches, and house sparrows were fed different formulations of IVM-treated bird feed and observed for clinical signs, and their sera were fed to Results: Speciation analyses conducted on blood meals from Conclusions: These results suggest that targeting songbirds with IVM-treated bird feed should be safe for wildlife and may elicit high rates of IVM-induced mortality by reaching a large proportion of WNV vector mosquitoes via their proclivity for feeding on passerine birds.

Indexed as

avian reservoir hostCulex tarsalisivermectinmosquito controlWest Nile viruswildlife self-medication

Identifiers

PMID41446104
PMCPMC12724676

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.