Evidence map›Paper›PMID 41446083›Full record

ArticlebioRxiv : the preprint server for biology2025

Reconstitution of antiviral Dicer activity in vitro reveals distinct contributions of RDE-4 dsRNA-binding motifs.

Elaina P Boyle, P Joseph Aruscavage, Claudia D Consalvo, Brenda L Bass

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Elaina P BoyleDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112.ORCID 0000-0003-2617-1054
P Joseph AruscavageDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112.
Claudia D ConsalvoDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112.ORCID 0000-0003-2038-4315
Brenda L BassDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112.ORCID 0000-0003-1728-2254

Funding

Elucidating roles and mechanisms of double-stranded RNA-mediated pathwaysR35GM141262 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Brenda L. Bass · 2021 to 2026
$3.7M
Q-ToF Mass Spectrometer for the University of Utah MS and Proteomics CoreS10OD018210 · OD · UNIVERSITY OF UTAH · PI COX, JAMES ERIC · 2015 to 2015
$530k
NIGMS NIH HHS R35 GM141262NIH HHS S10 OD018210
6 · The paper itself

Abstract

In

Indexed as

C. elegansDRH-1dsRBMdsRBPinnate immunityRNAi

Identifiers

PMID41446083
PMCPMC12724517

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.