Evidence map›Paper›PMID 41446050›Full record

ArticlebioRxiv : the preprint server for biology2025

Prion shedding is reduced by chronic wasting disease vaccination.

Hanaa Ahmed-Hassan, Dalia Abdelaziz, Yo-Ching Cheng, Kevin Low, Shirley Phan, Byron Kruger, Chimoné S Dalton, Lech Kaczmarczyk, Walker S Jackson, Sabine Gilch and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Hanaa Ahmed-HassanCalgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Dalia AbdelazizCalgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Yo-Ching ChengCalgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Kevin LowCalgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Shirley PhanCalgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Byron KrugerCalgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Chimoné S DaltonCalgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Lech KaczmarczykLinköping University, Linköping, Sweden.
Walker S JacksonLinköping University, Linköping, Sweden.ORCID 0000-0002-3003-5509
Sabine GilchCalgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Hermann M SchätzlCalgary Prion Research Unit, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-4972-8740

Funding

Chronic Wasting Disease VaccinesR01AI156037 · NIAID · COLORADO STATE UNIVERSITY · PI MATHIASON, CANDACE K. · 2021 to 2025
$3.5M
NIAID NIH HHS R01 AI156037
6 · The paper itself

Abstract

Chronic wasting disease (CWD) is a strictly fatal and highly contagious prion disease of wild and farmed cervids currently expanding in North America. Prion diseases are caused by conversion of the cellular prion protein to its pathological isoform PrP

Indexed as

cervidChronic wasting diseaseCWDfecal prionsprionprion sheddingprion vaccineurine prionsvaccine

Identifiers

PMID41446050
PMCPMC12724456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.