ArticlebioRxiv : the preprint server for biology2025
Insertion of rare autism variants in synaptic genes induce novel behavioral phenotypes in
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
Abstract
Neurodevelopmental conditions and disorders, including autism, involve a complex interplay of genetic, environmental, and developmental factors. Despite this complexity, genetic studies have identified more than 150 candidate genes that increase risk for autism and related neurodevelopmental and neuropsychiatric conditions. Unsurprisingly, synaptic genes are a large proportion of these genes, likely due to their roles in the formation and maintenance of synaptic architecture, function, and the plasticity of neurons and circuits. The association of synaptic genes with autism and similar conditions is driven by all types of genetic variation, including inherited and
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Registered trials
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