ArticleJHLT open2026
Demographic differences in complication and failure to rescue rates following lung transplantation.
Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
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Abstract
Background: We evaluated the association between race/ethnicity and failure to rescue (FTR) following lung transplantation. Methods: We conducted a retrospective cohort study of 34,184 patients undergoing primary lung transplantation (2006-2024). Race/ethnicity was categorized as non-Hispanic White (81.3%), non-Hispanic Black (9.5%), and Hispanic (9.1%). The primary outcome was FTR. Logistic regression identified predictors of FTR, while Cox proportional hazards models assessed the association between race/ethnicity and outcomes. Results: Black patients experienced the highest rates of postoperative complications (26.3%) compared to non-Hispanic White (17.9%) and Hispanic patients (19.6%) (p < 0.001). Mortality rate was also highest among Black patients (6.8%) compared to White (5.0%) and Hispanic patients (4.8%) (p <0.001). However, race/ethnicity was not independently associated with FTR. Risk factors for FTR included dialysis at transplant (OR 2.05, 95% CI: 1.28-3.29, p=0.003), double lung transplant (OR 1.30, 95% CI: 1.09-1.56, p=0.004), and prolonged ischemic time (OR 1.05, 95% CI: 1.02-1.08, p=0.001). Conclusions: While Black patients experienced higher complication and mortality rates, race/ethnicity was not independently linked to FTR after lung transplantation.
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