Evidence map›Paper›PMID 41445985›Full record

ArticleCureus2025

Progressive Supranuclear Palsy With Post-traumatic Frontal Lobe Damage Mimicking Anti-IgLON5 Antibody Disease.

Damla Ates Gulkok, Aiswarya Raj, Yakira Mishan, Jessica Bloom, Brittany Zaita, Robert Fekete

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Damla Ates GulkokNeurology, New York Medical College, Valhalla, USA.
Aiswarya RajNeurology, New York Medical College, Valhalla, USA.
Yakira MishanNeurology, New York Medical College, Valhalla, USA.
Jessica BloomNeurology, New York Medical College, Valhalla, USA.
Brittany ZaitaNeurology, New York Medical College, Valhalla, USA.
Robert FeketeNeurology, New York Medical College, Valhalla, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenotypic overlap between autoimmune encephalitis and movement disorders may rarely occur. We present a patient with progressive gait disturbance, vertical supranuclear gaze palsy, cognitive decline, and daytime somnolence, as well as extremity chorea. He was initially suspected of having autoimmune encephalitis. Antibody testing was negative in serum and cerebrospinal fluid. A fall leading to subdural hemorrhage and bilateral post-traumatic frontal lobe changes likely led to his bilateral upper and lower extremity involuntary movements. His mental status improved after lumbar puncture. His condition further improved on treatment with carbidopa levodopa 25/100 mg three times a day.  While the presentation of this case was suspicious for autoimmune encephalitis, the patient was diagnosed with progressive supranuclear palsy and traumatic encephalopathy with involuntary movements due to frontal lobe damage.

Indexed as

choreafrontal lobe injuryinvoluntary limb movementprogressive supranuclear palsypsp

Identifiers

PMID41445985
PMCPMC12723170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.