Evidence map›Paper›PMID 41445981›Full record

ArticleLaryngoscope investigative otolaryngology2025

Novel Combination Dexmedetomidine and Propofol Anesthetic Regimen for DISE Improves Procedural Efficiency Compared to Single-Agent Regimens.

Ryan Patrick, Ann Birmingham, Paul Allen, Sveta Karelsky

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan PatrickDepartment of Otolaryngology University of Rochester Medical Center Rochester New York USA.ORCID https://orcid.org/0009-0001-2800-5263
Ann BirminghamDepartment of Otolaryngology University of Rochester Medical Center Rochester New York USA.ORCID https://orcid.org/0009-0002-0355-3666
Paul AllenDepartment of Otolaryngology University of Rochester Medical Center Rochester New York USA.ORCID https://orcid.org/0000-0002-4924-4730
Sveta KarelskyDepartment of Otolaryngology University of Rochester Medical Center Rochester New York USA.ORCID https://orcid.org/0000-0002-7567-4275

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study examines a combination anesthetic regimen of propofol and dexmedetomidine during drug induced sleep endoscopy (DISE) and its procedure time, VOTE findings, and perioperative hemodynamic profiles when compared to procedures conducted with either anesthetic agent alone. Methods: Retrospective chart analysis of 407 patients undergoing DISE at a single institution with anesthetic regimens of dexmedetomidine alone, propofol alone, or a combination of both. Demographic information, DISE findings via VOTE scoring, and perioperative vital signs and timing intervals were compared. Results: With respect to operative time, the combination regimen cohort demonstrated an average operative time of 22.1 min, 14% shorter than the dexmedetomidine only (25.8 min; Conclusion: This novel combination anesthetic regimen of dexmedetomidine and propofol during DISE leads to increased procedural efficiency with preservation of vital sign stability. Level of Evidence: 3.

Indexed as

combination anesthesia regimenDISE anesthesia regimenDISE efficiency

Identifiers

PMID41445981
PMCPMC12723316

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.