Evidence map›Paper›PMID 41445904›Full record

ArticleSouth Asian journal of cancer2025

Immunohistochemical Subclassification of Peripheral T Cell Lymphomas-Not Otherwise Specified.

Keerthana Chandran, Indu R Nair, Pavithran Keechilat

Abstract read
In one paragraph

Article in South Asian journal of cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Keerthana ChandranDepartment of Pathology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.ORCID 0000-0002-6234-8462
Indu R NairDepartment of Pathology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.ORCID 0000-0002-4846-4037
Pavithran KeechilatDepartment of Medical Oncology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.ORCID 0000-0002-6129-5709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Peripheral T cell lymphomas-not otherwise specified (PTCL-NOS) are a heterogeneous group of mature T cell lymphomas that do not belong to any specified subtype. Gene expression profiling has revealed two biological variants of PTCL-NOS, PTCLGATA3 and PTCLTBX21. This study aims to subclassify PTCL-NOS using immunohistochemistry (IHC) and to establish its implication in prognosis. Methods: A descriptive study was done using 39 morphologically and immunohistochemically diagnosed cases of PTCL diagnosed over a 10-year period, 2013 to 2022. The additional IHC markers used were GATA3 and CCR4 for PTCLGATA3 and TBX21 and CXCR3 for PTCLTBX21. All cases had a minimum follow-up of 6 months. Results: After subclassification of PTCL-NOS ( Conclusion: Subcategorization of PTCL-NOS based on the IHC markers helps in the stratification of this disease. This will also identify cases with more aggressive behavior at the time of diagnosis.

Indexed as

IHC-GATA-3prognosisPTCLsubclassification

Identifiers

PMID41445904
PMCPMC12727040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.