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ArticleFrontiers in cardiovascular medicine2025

Uncommon association of coronary artery ectasia and myocardial bridge presenting as non-ST-segment elevation myocardial infarction: a case report.

Marlon Rojas-Cadena, Felipe Rodríguez-Arcentales, Colon Arteaga, Sylvia Davila, Juan Carlos Gaibor, Juan S Izquierdo-Condoy

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Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Marlon Rojas-CadenaOne Health Research Group, Faculty of Medicine, Universidad de las Américas, Quito, Ecuador.
Felipe Rodríguez-ArcentalesDepartment of Cardiology, Hospital de Especialidades Carlos Andrade Marín, Quito, Ecuador.
Colon ArteagaDepartment of Cardiology, Hospital de Especialidades Carlos Andrade Marín, Quito, Ecuador.
Sylvia DavilaDepartment of Cardiology, Hospital de Especialidades Carlos Andrade Marín, Quito, Ecuador.
Juan Carlos GaiborDepartment of Cardiology, Hospital Metropolitano, Quito, Ecuador.
Juan S Izquierdo-CondoyOne Health Research Group, Faculty of Medicine, Universidad de las Américas, Quito, Ecuador.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Coronary artery ectasia (CAE)-diffuse dilatation ≥1.5× the adjacent segments is uncommon and lacks standardized management. Its coexistence with a hemodynamically significant myocardial bridge (MB) is unusual and may create competing disturbances in coronary flow that complicate diagnosis and treatment. Case presentation: An 80-year-old man with hypothyroidism, epilepsy, benign prostatic hyperplasia, and paroxysmal atrial fibrillation on rivaroxaban presented with acute precordial pain consistent with non-ST-segment elevation myocardial infarction (NSTEMI). He was hemodynamically stable; ECG showed inferior ST depression with T-wave inversion in V3-V4, and high-sensitivity troponin was elevated (Killip I, GRACE 177, CRUSADE 49). Early diagnostic angiography (<24 h) revealed diffuse three-vessel ectasia (Markis I) with slow TIMI-2 flow and a prominent mid-LAD MB (∼75% systolic "milking"); the intermediate branch had an ostial lesion with downstream aneurysmal dilatation and was not amenable to PCI. Echocardiography showed LVEF >65% with basal inferior/inferoseptal hypokinesia and severe left-atrial enlargement (57 ml/m Conclusions: Diffuse CAE with significant MB can precipitate NSTEMI without discrete obstructive lesions and challenges standard revascularization. In such anatomy, individualized conservative therapy-rate control and tailored antithrombotic management-may be preferable, while advanced imaging and diastolic physiology can refine diagnosis and selection for invasive strategies.

Indexed as

antithrombotic therapyconservative managementcoronary artery ectasiamyocardial bridgingNSTEMI

Identifiers

PMID41445865
PMCPMC12722803

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