ArticleFrontiers in oncology2025
Prognostic value of serum free light chain abnormalities in diffuse large B-cell lymphoma.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: This study aimed to evaluate the prognostic significance of serum free light chain (FLC) abnormalities in patients diagnosed with diffuse large B-cell lymphoma (DLBCL), with an emphasis on associations with clinical characteristics and survival outcomes. Methods: This retrospective study included 259 patients newly diagnosed with DLBCL. Serum FLC levels in patients diagnosed with DLBCL were measured prior to the initiation of chemotherapy. Results: Comparing to normal FLC, abnormal serum FLC levels were significantly associated with several clinical features including age > 60 years ( Conclusions: Abnormal serum FLC levels were associated with adverse clinical features and inferior survival outcomes in DLBCL, particularly monoclonal FLC in the non-GCB subtype. These findings support the utility of serum FLC assessment as a simple, accessible biomarker for risk stratification in DLBCL, though it was not confirmed as an independent risk factor in multivariate analysis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.