Evidence map›Paper›PMID 41445668›Full record

ArticlemedRxiv : the preprint server for health sciences2025

MOG1

Paula G Socuéllamos, Juan Manuel Ruiz-Robles, Francisco M Cruz, Álvaro Macías, Alba Vera-Zambrano, Ana I Moreno-Manuel, Carmen Prior, Antonio J Cartón, Carmen Valenzuela, José Jalife

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paula G SocuéllamosSpanish National Center for Cardiovascular Research (CNIC), Madrid, Spain.ORCID 0000-0001-7097-1708
Juan Manuel Ruiz-RoblesSpanish National Center for Cardiovascular Research (CNIC), Madrid, Spain.ORCID 0000-0002-0566-9315
Francisco M CruzSpanish National Center for Cardiovascular Research (CNIC), Madrid, Spain.
Álvaro MacíasSpanish National Center for Cardiovascular Research (CNIC), Madrid, Spain.
Alba Vera-ZambranoInstituto de Investigaciones Biomédicas Sols-Morreale (CSIC-UAM), Madrid, Spain.
Ana I Moreno-ManuelSpanish National Center for Cardiovascular Research (CNIC), Madrid, Spain.ORCID 0000-0002-5011-2786
Carmen PriorHospital Universitario La Paz, Madrid, Spain.
Antonio J CartónHospital Universitario La Paz, Madrid, Spain.ORCID 0000-0002-3429-0419
Carmen ValenzuelaInstituto de Investigaciones Biomédicas Sols-Morreale (CSIC-UAM), Madrid, Spain.ORCID 0000-0003-3929-1960
José JalifeSpanish National Center for Cardiovascular Research (CNIC), Madrid, Spain.ORCID 0000-0003-0080-3500

Funding

Peptibodies As Novel Therapies in Atrial FibrillationR01HL163943 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI Sami Fouad Noujaim, MICHAEL N TENG · 2023 to 2026
$2.4M
NHLBI NIH HHS R01 HL163943NIMHD NIH HHS L60 MD007229
6 · The paper itself

Abstract

Background: Na Methods: We identified the first variant of unknown significance (VUS) in MOG1 (g.52C>T; p.18L>F) in a proband with LQTS. We generated AAV9-mediated cardiac-specific mouse models expressing MOG1 Results: Clinical data from the MOG1 Conclusion: We have uncovered a new genetic basis for LQTS. Our findings demonstrate that the MOG1

Indexed as

ArrhythmiasLate sodium currentLong QT syndromeMOG1

Identifiers

PMID41445668
PMCPMC12723964

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.