Evidence map›Paper›PMID 41445648›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Acute post-stroke cognitive test performance predicts one-year functional independence.

Alan Romanowski, Kathleen Langbehn, Maurizio Corbetta, Daniel Tranel, Aaron D Boes, Mark Bowren

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alan RomanowskiDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa, USA.ORCID 0009-0008-8141-9087
Kathleen LangbehnDepartment of Neurology, Carver College of Medicine, University of Iowa, Iowa, USA.ORCID 0000-0001-6875-6320
Maurizio CorbettaDepartment of Neuroscience, Venetian Institute of Molecular Medicine, Italy.ORCID 0000-0001-8295-3304
Daniel TranelDepartment of Neurology, Carver College of Medicine, University of Iowa, Iowa, USA.ORCID 0000-0002-1338-1389
Aaron D BoesDepartment of Pediatrics, Carver College of Medicine, University of Iowa, Iowa, USA.ORCID 0000-0002-7865-9257
Mark BowrenDepartment of Neurology, Carver College of Medicine, University of Iowa, Iowa, USA.ORCID 0000-0003-3304-6921

Funding

NATIONAL RESEARCH SERVICE AWARD-MEDICAL SCIENTISTT32GM007200 · NIGMS · WASHINGTON UNIVERSITY · PI YOKOYAMA, WAYNE M. · 1985 to 2024
$59.8M
The Neurobiology of Social Decision-Making: Social Inference and ContextP50MH094258 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ADOLPHS, RALPH · 2012 to 2021
$18.6M
University of Iowam - Whole Body 7T MRI ScannerS10RR028821 · NCRR · UNIVERSITY OF IOWA · PI MAGNOTTA, VINCENT A · 2010 to 2010
$8.0M
The Iowa Neuroscience Specialty Program in Research Education (INSPIRE)T32MH019113 · NIMH · UNIVERSITY OF IOWA · PI HANNA E STEVENS, John A Wemmie · 1991 to 2026
$5.6M
Translation of in-clinic Gains to Gains in Daily Life After StrokeR01HD068290 · NICHD · WASHINGTON UNIVERSITY · PI LANG, CATHERINE · 2012 to 2021
$4.0M
Stroke, Brain Networks, and BehaviorR01NS095741 · NINDS · WASHINGTON UNIVERSITY · PI CORBETTA, MAURIZIO · 2015 to 2019
$3.0M
UNDERSTANDING THE EFFECTS OF STROKE USING FUNCTIONAL CONNECTIVITY MRIR01HD061117 · NICHD · WASHINGTON UNIVERSITY · PI CORBETTA, MAURIZIO · 2009 to 2013
$2.8M
Predicting Cognitive Outcomes from Stroke Based on Lesion LocationR01NS114405 · NINDS · UNIVERSITY OF IOWA · PI BOES, AARON D · 2020 to 2024
$2.1M
Mechanisms of Health and Disease at the Behavioral-Biomedical InterfaceT32GM108540 · NIGMS · UNIVERSITY OF IOWA · PI LUTGENDORF, SUSAN K, VOSS, MICHELLE WEBB · 2014 to 2023
$1.7M
Investigating the Effects of Transcranial Magnetic Stimulation with Intracranial EEG in HumansR21MH120441 · NIMH · UNIVERSITY OF IOWA · PI BOES, AARON D, OYA, HIROYUKI · 2019 to 2020
$425k
THE ELECTROPHYSIOLOGY OF RESTING STATE FMRI NETWORKSF30MH099877 · NIMH · WASHINGTON UNIVERSITY · PI HACKER, CARL · 2013 to 2017
$176k
NCRR NIH HHS S10 RR028821NICHD NIH HHS R01 HD061117NICHD NIH HHS R01 HD068290NIGMS NIH HHS T32 GM007200NIGMS NIH HHS T32 GM108540NIMH NIH HHS F30 MH099877NIMH NIH HHS P50 MH094258NIMH NIH HHS R21 MH120441NIMH NIH HHS T32 MH019113NINDS NIH HHS R01 NS095741NINDS NIH HHS R01 NS114405
6 · The paper itself

Abstract

Objective: General cognitive ability (g), a latent variable derived from cognitive data, can predict life outcomes (e.g., educational attainment and occupational success) among neurologically healthy individuals. The value of g for predicting post-stroke functional outcomes is unknown. We addressed this gap here. Method: We derived g using exploratory structural equation modeling of 15 neuropsychological tests administered to 112 patients with stroke, 69 of whom also had functional outcome data (42 men; mean age = 53.23 years (SD = 10.54)). We used logistic regressions to compare g and individual tests in terms of their ability to predict the Functional Assessment Measure (FAM) and the Functional Independence Measure (FIM; motor and cognitive subscales) at 12 months post-stroke. Results: g was a statistically significant predictor of FAM ( Conclusions: Acute measures of cognition, including g, can predict functional independence 12 months after stroke. g and visuospatial ability measures were the most robust predictors.

Indexed as

Functional OutcomesFunctional StatusGeneral Cognitive AbilityNeuropsychologyStrokeStroke Rehabilitation

Identifiers

PMID41445648
PMCPMC12723970

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.