Evidence map›Paper›PMID 41445563›Full record

ArticlemicroPublication biology2025

DHEA inhibits regeneration in

Erin Frank, Iris Pardue, Ifti Rahman, Emily Banthin, Kathy Gillen

Abstract read
In one paragraph

Article in microPublication biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erin Frank *Molecular Biology, Kenyon College, Gambier, Ohio, United States.
Iris Pardue *Molecular Biology, Kenyon College, Gambier, Ohio, United States.
Ifti Rahman *Molecular Biology, Kenyon College, Gambier, Ohio, United States.
Emily BanthinBiology, Kenyon College, Gambier, Ohio, United States.
Kathy GillenBiology, Kenyon College, Gambier, Ohio, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some organisms can regrow severed body parts. In vertebrates, the anabolic pentose phosphate pathway (PPP) aids regeneration, but we do not know if invertebrates require the PPP for regeneration. To test this, we attempted to inhibit the PPP rate limiting enzyme, glucose-6-phosphate dehydrogenase (G6PD), with the steroid dehydroepiandrosterone (DHEA), using the regenerative annelid

Identifiers

PMID41445563
PMCPMC12723521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.