Evidence map›Paper›PMID 41445558›Full record

ArticleJBMR plus2025

Harmonized Tubular Maximum Phosphate reabsorption per Glomerular Filtration Rate reporting in adults and children in Australia and New Zealand.

Cherie Chiang, Kay Weng Choy, Penelope Coates, Simon Carrivick, Christopher J Farrell, Roderick J Clifton-Bligh, Ee Mun Lim

Abstract read
In one paragraph

Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cherie ChiangDepartment of Medicine, University of Melbourne, Parkville, VIC 3050, Australia.
Kay Weng ChoyDepartment of Pathology, Northern Health, Epping, VIC 3076, Australia.
Penelope CoatesDepartment of Chemical Pathology, SA Pathology, Adelaide, SA 5000, Australia.
Simon CarrivickDepartment of Biochemistry, Pathwest QEII Medical Centre, Nedlands, SA 6009  Australia.
Christopher J FarrellNew South Wales Health Pathology, Liverpool Hospital, Liverpool, NSW 2170, Australia.
Roderick J Clifton-BlighDepartment of Endocrinology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Ee Mun LimDepartment of Biochemistry, Pathwest QEII Medical Centre, Nedlands, SA 6009  Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tubular maximum phosphate reabsorption per glomerular filtration rate (TmP/GFR) is a key diagnostic test for renal phosphate wasting. However, there is a lack of international consensus regarding the reporting of age-related reference intervals. The TmP/GFR Harmonization Working Group, formed by The Australasian Association for Clinical Biochemistry (AACB) and Laboratory Medicine and The Australian and New Zealand Bone and Mineral Society (ANZBMS), aimed to evaluate analytical differences amongst commercial creatinine and phosphate assays, harmonize age-specific cut-offs and compare the ANZBMS TmP/GFR online calculator with existing products. A total of 11 360 results from The Royal College of Pathologists of Australasia Quality Assurance Programs were analyzed to assess creatinine and phosphate assay performance amongst 5 in vitro diagnostic (IVD) companies. Ortho-Clinical Diagnostics analyzers had a positive bias of up to 32% for serum phosphate and up to 29% for TmP/GFR. The other IVD companies produced comparable results and are suitable for harmonized reference intervals. To date, the AACB-ANZBMS TmP/GFR online calculator is the only validated Isotope Dilution Mass Spectrometry-creatinine aligned tool which caters for both pediatric and adult individuals, providing automatic interpretive comments to aid clinicians managing patients with hypophosphatemia.

Indexed as

hypophosphatemiaonline calculatorosteomalaciatubular maximum phosphate reabsorption per glomerular filtration rateX-linked hypophosphatemia (XLH)

Identifiers

PMID41445558
PMCPMC12723803

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.