Evidence map›Paper›PMID 41445551›Full record

ArticleJBMR plus2025

A retrospective analysis of the prevalence of hypophosphatemia and hypocalcemia after intravenous iron polymaltose in the inpatient setting.

Lauren C Burrage, Stacey Llewellyn, Leanne Foyn, Carel Pretorius, Syndia Lazarus

Abstract read
In one paragraph

Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lauren C BurrageDepartment of Endocrinology and Diabetes, Royal Brisbane and Women's Hospital, Brisbane, QLD 4029, Australia.
Stacey LlewellynQIMR Berghofer, Brisbane, QLD 4006, Australia.
Leanne FoynDepartment of Chemical Pathology, Pathology Queensland, Brisbane, QLD 4029, Australia.
Carel PretoriusFaculty of Medicine, The University of Queensland, Brisbane, QLD 4006, Australia.
Syndia LazarusDepartment of Endocrinology and Diabetes, Royal Brisbane and Women's Hospital, Brisbane, QLD 4029, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypophosphatemia occurring after ferric carboxymaltose or iron polymaltose infusion is common and has been well-characterized. Post-iron infusion hypocalcemia has been documented in case reports, but there is no data on the prevalence of hypocalcemia developing after i.v. iron infusion. In this retrospective cohort study, we sought to characterize integrated daily changes in serum phosphate and corrected calcium levels before and after iron infusion in a real-world inpatient setting. Inpatients who received i.v. iron polymaltose at the Royal Brisbane and Women's Hospital (Queensland, Australia) between January 2020 and September 2021 were included. We extracted all results for serum phosphate and corrected calcium levels for 21 d before and after iron infusion. A total of 741 patients with 8272 blood samples were included. The serum phosphate concentration reduced by an average of 30.6% (95% CI 28.2-32.9) in the 5 d following infusion. Serum phosphate reached a nadir at day 5 before incrementing, but still remained below baseline by the end of the study period. Conversely, serum corrected calcium levels increased within 1 d of iron polymaltose infusion and then dropped over the following 5 d. There was a significant increase in the prevalence of hypophosphatemia developing after iron polymaltose infusion (34% post-infusion vs 8% pre-infusion,

Indexed as

ferric carboxymaltoseFGF23hypocalcemiahypophosphatemiairon polymaltosei.v. iron infusion

Identifiers

PMID41445551
PMCPMC12723662

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.