Evidence map›Paper›PMID 41444967›Full record

ArticleChild and adolescent psychiatry and mental health2025

Adverse childhood experiences and adolescent externalizing and internalizing problems in the ELSPAC-CZ cohort.

Gabriela Ksinan Jiskrova, Albert J Ksinan, Hynek Pikhart, Martin Bobák, Jana Klanova, Rebecca E Lacey

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Article in Child and adolescent psychiatry and mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Gabriela Ksinan JiskrovaRECETOX, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic. gabriela.ksinanova@recetox.muni.cz.
Albert J KsinanRECETOX, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.
Hynek PikhartRECETOX, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.
Martin BobákRECETOX, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.
Jana KlanovaRECETOX, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.
Rebecca E LaceySchool of Health & Medical Sciences, City St George's, University of London, London, UK.

Funding

European Union-Next Generation EU LX22NPO5101European Union's Horizon 2020 No. 857487 and No. 857560
6 · The paper itself

Abstract

backgroundExposure to adverse childhood experiences (ACEs) has been linked to mental health difficulties later in life. However, much of the existing research relies on cross-sectional designs and retrospectively reported ACEs, which are susceptible to recall bias and confounding by early life factors, such as family socioeconomic status or childhood temperament. Moreover, the majority of these studies have been conducted in the United States and the United Kingdom, limiting the generalizability of their findings. To address these limitations, we examined the association between prospectively measured ACEs and adolescent adjustment using data from a longitudinal, population-based birth cohort in Central Europe.

methodsData were obtained from the Czech part of the European Longitudinal Cohort Study of Pregnancy and Childhood (ELSPAC-CZ; N = 2,741). ACE score was calculated as a sum of eight intra-familial adversities assessed prospectively between 6 months and 11 years postpartum. Adolescent internalizing and externalizing problems were measured via Strength and Difficulties Questionnaire (SDQ) at 11 years and were reported by adolescents and their mothers.

resultsLinear regression models showed that ACE score was associated with internalizing problems reported by adolescent (β = 0.063, 95% CI [0.019, 0.107]) and mother (β = 0.120, 95% CI [0.077, 0.163]), and externalizing problems reported by adolescent (β = 0.088, 95% CI [0.045, 0.132]) and mother (β = 0.114, 95% CI [0.072, 0.157]). The association was driven particularly by physical and emotional abuse.

conclusionsACE were common in ELSPAC-CZ sample (69% of children experienced at least one ACE) and were prospectively associated with adjustment in adolescents, independently from family socioeconomic status, prenatal and birth characteristics, and early childhood temperament, suggesting a robust link between ACE and adolescent adjustment.

Indexed as

ACE scoreAdverse childhood experiencesEuropean longitudinal study of pregnancy and childhoodExternalizingInternalizing

Identifiers

PMID41444967
PMCPMC12849584

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