Evidence map›Paper›PMID 41444922›Full record

SynthesisJournal of cardiothoracic surgery2025

Extra-corporeal-cardiopulmonary-resuscitation vs. conventional-cardiopulmonary-resuscitation: an in-depth look into short- and long-term neurological outcomes.

Farah Yasmin, Asad Ur Rab, Afia Salman, Muhammad Ahmed Ali Fahim, Hafsah Alim Ur Rahman, Abdul Moeed, Eman Ali, Muhammad Sohaib Asghar, Iqbal Ratnani, Salim Surani

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Farah YasminYale School of Medicine, New Haven, CT, USA.
Asad Ur RabFoundation University Medical College, Islamabad, Pakistan.
Afia SalmanDow University of Health Sciences, Karachi, Pakistan.
Muhammad Ahmed Ali FahimDow University of Health Sciences, Karachi, Pakistan.
Hafsah Alim Ur RahmanDow University of Health Sciences, Karachi, Pakistan.
Abdul MoeedDow University of Health Sciences, Karachi, Pakistan.
Eman AliDow University of Health Sciences, Karachi, Pakistan.
Muhammad Sohaib AsgharAdvent Health, Sebring, FL, USA. msohaibasghar123@gmail.com.
Iqbal RatnaniHouston Methodist Hospital, Houston, TX, USA.
Salim SuraniTexas A&M University, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtracorporeal cardiopulmonary resuscitation (eCPR) is a new approach for cardiac arrest management and is regarded as a possible alternative for conventional cardiopulmonary resuscitation (cCPR).

aimOur systematic review and meta-analysis seek to compare outcomes of cCPR versus eCPR in patients with out-of-hospital cardiac arrest (OHCA).

methodsPreferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed in this study and the questionnaire utilized the PICO (Patient, Intervention, Control, Outcome) framework. A search strategy using MeSH (Medical Subject Headings) terms was made from which Pubmed/Medline, SCOPUS, and Cochrane Library were searched from inception till March 2024 to reveal all relevant studies. Conference proceedings, www. CLINICALTRIALS: gov , and bibliometrics of published articles were also searched for gray literature.

resultsCompared with conventional CPR (cCPR), extracorporeal CPR (eCPR) was associated with higher odds of favorable neurological outcome at discharge (OR 2.61, 95% CI 1.28-5.32; p = 0.008; I²=82%), 3-months (OR 3.29, 95% CI 1.63-6.63; p = 0.0009; I²=46%), and 6-months (OR 1.97, 95% CI 1.24-3.12; p = 0.004; I²=12%). The increase at 1-month was not significant (OR 2.15, 95% CI 0.87-5.34; p = 0.10; I²=90%). eCPR also improved survival-to-discharge (OR 1.84, 95% CI 1.17-2.92; p = 0.009; I²=73%).

conclusioneCPR in the management of OHCA patients has more favorable neurological and survival outcomes as compared to cCPR.

Indexed as

Cardiopulmonary ResuscitationExtracorporeal Membrane OxygenationOut-of-Hospital Cardiac ArrestHumansTime FactorsTreatment OutcomeCardiopulmonary resuscitationCerebral performance categoriesExtracorporeal cardiopulmonary resuscitation

Identifiers

PMID41444922
PMCPMC12729085

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.