Evidence map›Paper›PMID 41444884›Full record

SynthesisBMC medical informatics and decision making2025

Application of artificial intelligence tools and clinical documentation burden: a systematic review and meta-analysis.

Jungang Zhao, Hanxiang Liu, Yaolong Chen, Fujian Song

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC medical informatics and decision making, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Artificial intelligence in clinical genetics: Current practice and attitudes among the clinical genetics workforce.Genetics in medicine : official journal of the American College of Medical Genetics · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. The augmented physician: AI and the future of clinical cognition.Frontiers in artificial intelligence · 2026
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jungang ZhaoDepartment of Pediatric Research Institute, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.
Hanxiang LiuDepartment of Pediatric Research Institute, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.
Yaolong ChenDepartment of Pediatric Research Institute, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China. 483861@hospital.cqmu.edu.cn.
Fujian SongDepartment of Pediatric Research Institute, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China. fujian.song@uea.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinician burnout is a growing global concern, with heavy clinical documentation workload identified as a major contributor. Clinical documentation tasks, though essential for patient care and communication, are time-consuming and cognitively demanding. Recent advances in artificial intelligence (AI), particularly natural language processing and large language models, are being explored as potential tools to alleviate documentation burden, yet their quantitative impact has not been systematically assessed.

methodsWe performed a systematic review and meta-analysis, registered on PROSPERO (CRD420250653291) and guided by PRISMA. Eligible studies included frontline health professionals using AI tools for clinical note creation, with comparators being usual practice or pre-implementation baseline. Primary outcomes were documentation burden, workload, burnout, and time spent on documentation. Searches were conducted in PubMed, Web of Science, Scopus, and key journals. Effect sizes were synthesized using standardized mean difference (SMD) under a random-effects model, with subgroup analyses by study design, AI tool type, task type, editing status, and data origin.

resultsOf the 23 studies included, 12 were non-randomised studies with a concurrent control and 11 employed a before-and-after comparison design. The study participants varied in specialties and were mainly from ambulatory settings, including physicians, surgeons, pediatricians, and ICU specialists. Heterogeneity in results across included studies was considerable, and the methodological quality of the available studies was generally low. Pooling results of the 14 studies yielded an overall standardized mean difference (SMD) of -0.71 (95% confidence interval [CI]: -0.93 to -0.49), indicating a moderate reduction in documentation workload and related burnout. Based on results of studies in which clinicians reviewed and edited AI-generated drafts, AI applications reduced documentation time, similarly representing a moderate effect size (SMD= -0.72, 95% CI -0.99 to -0.45). The quality of notes generated by AI tools was at least comparable to those prepared manually by clinicians.

conclusionsAI technologies offer promising benefits for reducing clinical documentation burden. However, their implementation must be accompanied by rigorous quality control and ongoing evaluation in practical settings to optimize their effectiveness and safeguard patient care outcomes.

Indexed as

Artificial IntelligenceBurnout, ProfessionalDocumentationWorkloadHumansNatural Language ProcessingArtificial IntelligenceBurnoutClinical DocumentationHealthcare workersLarge Language ModelsWorkload

Identifiers

PMID41444884
PMCPMC12836966

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.