Evidence map›Paper›PMID 41444868›Full record

ArticleBMC emergency medicine2025

Respiratory support during neonatal and infant aeromedical interfacility transfers in the Western Cape, South Africa: a retrospective review.

Andrit Lourens, Johanna Catharina Botha, Garth Moys, Cally Stephen, Nikita Werthmann, Jocelyn Park-Ross, Sandi Holgate

Abstract read
In one paragraph

Article in BMC emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrit LourensDivision of Emergency Medicine, Department of Family, Community and Emergency Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. andrit.lourens@uct.ac.za.ORCID 0000-0003-0180-6017
Johanna Catharina BothaDepartment of Clinical Health Sciences, School of Health Sciences, Faculty of Health, Natural Resources and Applied Sciences, Namibia University of Science and Technology, Windhoek, Namibia.ORCID 0000-0001-8367-805X
Garth MoysSouth African Red Cross Air Mercy Service, Cape Town, South Africa.ORCID 0009-0009-7274-9049
Cally StephenSouth African Red Cross Air Mercy Service, Cape Town, South Africa.
Nikita WerthmannSouth African Red Cross Air Mercy Service, Cape Town, South Africa.
Jocelyn Park-RossDivision of Critical Care, Department of Anaesthesia and Perioperative Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-8444-9141
Sandi HolgateDepartment of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.ORCID 0009-0002-6057-5001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInterfacility transfer (IFT) of neonates and infants is common in South Africa, with many needing respiratory support. Recently, interest in non-invasive ventilation, particularly nasal continuous positive airway pressure (nCPAP), during IFTs has increased; however, local evidence is limited. This study aimed to describe the characteristics of neonates and infants requiring respiratory support and to evaluate the introduction of nCPAP during IFTs by the South African Red Cross Air Mercy Service (AMS) in the Western Cape between 2017 and 2019.

methodsA retrospective descriptive review of all neonates (≤ 28 days) and infants ( > 28 days to ≤ 1 year) requiring respiratory support during AMS IFTs was conducted between 2017 and 2019.

resultsRespiratory support was required for 70.4% (435/618) of all neonates and infants transported during the study period. Of the 435 IFTs, 61.4% (n = 267) were neonates and 51.9% (n = 224) males. Approximately two-thirds (n = 296, 68.0%) were transported by rotor-wing (RW) aircraft, and Emergency Care Practitioners (n = 344, 79.1%) were the most common primary crew member. The median stabilisation time for RW and fixed-wing (FW) aircraft IFTs was > 60 mins, with median RW mission times approximately 3 hrs and > 5.5 hrs for FW. Common diagnoses included respiratory distress syndrome in neonates and pneumonia in infants. During IFTs, 174 (40.0%) patients received oxygen (O

conclusionThis study highlights the frequency of neonatal and infant aeromedical IFTs requiring respiratory support and the increasing adoption of nCPAP during aeromedical IFTs in one South African province. The findings suggest that nCPAP is a feasible respiratory support modality in the aeromedical IFT context; however, the safe and effective implementation relies on careful patient selection, adequately trained personnel, and appropriate equipment. Further research is warranted to evaluate the overall safety and clinical outcomes of nCPAP during IFTs and develop robust protocols and guidelines tailored to the South African context.

Indexed as

Air AmbulancesContinuous Positive Airway PressureNoninvasive VentilationPatient TransferFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesSouth AfricaAeromedicalContinuous Positive Airway Pressure [Mesh]Infant, Newborn [Mesh]InfantsInterfacility transfers (IFTs)nasal Continuous Positive Airway Pressure (nCPAP)NeonatesRespiratory support

Identifiers

PMID41444868
PMCPMC12728987

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.