Evidence map›Paper›PMID 41444671›Full record

ArticleAntimicrobial resistance and infection control2025

Sepsis outbreak following a probable extrinsic contamination of propofol by Escherichia coli, Geneva, 2024.

Roberta Petrucci, Amir Allaoua, Aliki Metsini, Abdessalam Cherkaoui, Diem-Lan Vu, Vladimir Lazarevic, Delphine Perreard, Nechan Haroutunian, Sophie Garcin, Olivier Grosgurin and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial resistance and infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Roberta PetrucciCantonal Physician's Office, Cantonal Health Department, Geneva, Switzerland. roberta.petrucci@etat.ge.ch.
Amir AllaouaDivision of Emergency Medicine, Department of Acute Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
Aliki MetsiniCantonal Physician's Office, Cantonal Health Department, Geneva, Switzerland.
Abdessalam CherkaouiBacteriology Laboratory, Division of Laboratory Medicine, Department of Diagnostics, Geneva University Hospitals, Geneva, Switzerland.
Diem-Lan VuCantonal Physician's Office, Cantonal Health Department, Geneva, Switzerland.
Vladimir LazarevicGenomic Research Laboratory, Department of Medicine, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
Delphine PerreardInfection Control Program, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
Nechan HaroutunianDivision of Emergency Medicine, Department of Acute Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
Sophie GarcinDivision of Emergency Medicine, Department of Acute Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
Olivier GrosgurinDivision of Emergency Medicine, Department of Acute Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
Nathalie VernazCantonal Pharmacist's Office, Cantonal Health Department, Geneva, Switzerland.
Stephan HarbarthInfection Control Program, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
Simon RegardCantonal Physician's Office, Cantonal Health Department, Geneva, Switzerland.
Jacques SchrenzelBacteriology Laboratory, Division of Laboratory Medicine, Department of Diagnostics, Geneva University Hospitals, Geneva, Switzerland.
Alessandro CassiniCantonal Physician's Office, Cantonal Health Department, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over a 14-day period, four patients developed sepsis within hours of undergoing endoscopic procedures at a gastroenterology outpatient clinic in Geneva (Switzerland), triggering an urgent epidemiological investigation upon notification to authorities. The case clustering raised concerns about a iatrogenic source, prompting a coordinated public health response. This report outlines the investigation led by the Geneva Health Authorities in collaboration with the medical team, emergency care providers, infection prevention specialists, and the bacteriology laboratory at Geneva University Hospitals. A multidisciplinary team, including an epidemiologist, a pharmacist and an infection prevention specialist, conducted an on-site investigation the day after the outbreak was identified, highlighting a probable extrinsic contamination of propofol by Escherichia coli.

Indexed as

Disease OutbreaksDrug ContaminationEscherichia coliEscherichia coli InfectionsPropofolSepsisAgedFemaleHumansMaleMiddle AgedSwitzerlandPropofol

Identifiers

PMID41444671
PMCPMC12729812

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.