Evidence map›Paper›PMID 41444548›Full record

ArticleBMC pregnancy and childbirth2025

Risk factors for obstetric anal sphincter injury: an exploratory Norwegian regional cohort study including amniotomy as a potential novel determinant.

Ida Elisabeth Bang, Kjersti Sletten Bakken, Mads Nikolaj Holten-Andersen

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Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ida Elisabeth BangWomen's Clinic, Innlandet Hospital Trust, Lillehammer, Norway.
Kjersti Sletten BakkenWomen's Clinic, Innlandet Hospital Trust, Lillehammer, Norway.
Mads Nikolaj Holten-AndersenDepartment of Pediatrics, Innlandet Hospital Trust, Lillehammer Hospital, Anders Sandvigs Gate 17, 2609, Lillehammer, Norway. madsn.holten-andersen@sykehuset-innlandet.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObstetric anal sphincter injury refers to the unintended tearing of the anal sphincter and/or rectal mucosa during vaginal delivery, a complication associated with significant morbidity. Well-known risk factors for obstetric anal sphincter injury include primiparity, high maternal age, instrumental delivery, oxytocin augmentation, and large fetal size. Recently, we identified amniotomy as a potential novel independent risk factor, regardless of parity. This study aims to further explore whether amniotomy increases the risk of obstetric anal sphincter injury including known determinants in singleton vaginal births after 34 weeks of gestation at Innlandet Hospital Trust, using a cohort study design.

methodsRetrospective cohort study using data from the Innlandet Perinatal Database, including all women who had singleton vaginal births after 34 weeks of gestation at Innlandet Hospital Trust from 2012 to 2022. We used multivariate logistic regression models to develop a risk-factor model for obstetric anal sphincter injury employing backward elimination with stratification for parity. We included established risk factors in the models, as well as the novel potential risk factor amniotomy.

resultsThe annual incidence of obstetric anal sphincter injury at the hospitals was stable around 2% in the study period and a total of 26,349 births were included. First, amniotomy was not found to be a risk factor for obstetric anal sphincter injury in this contemporary cohort. Second, instrumental delivery was identified as an independent modifiable risk factor for obstetric anal sphincter injury: vacuum extraction presenting relative risks (95% CI) of 2.72 (2.06-3.61) and 3.29 (2.09-5.17) in vaginally primiparous and parous women and forceps 5.97 (3.96-9.00) in vaginally primiparous women. Episiotomy and epidural analgesia were associated with reduced risks of obstetric anal sphincter injury, but only in vaginally primiparous women (relative risks: 0.53 (0.40-0.70) and 0.69 (0.55-0.86)).

conclusionsBased on systematically collected data from our regional birth registry, this cohort study confirmed the association between established risk factors for obstetric anal sphincter injury, such as instrumental vaginal delivery. However, we could not identify amniotomy as a risk factor for obstetric anal sphincter injury, possibly due to changes in clinical practice and potential data limitations.

Indexed as

AmniotomyAnal CanalDelivery, ObstetricLacerationsObstetric Labor ComplicationsAdultFemaleHumansIncidenceNorwayParityPregnancyRetrospective StudiesRisk FactorsAmniotomyInstrumental deliveryOASIParityRisk factor

Identifiers

PMID41444548
PMCPMC12739843

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