Evidence map›Paper›PMID 41444505›Full record

SynthesisBMC geriatrics2025

Non-pharmacological interventions for managing acute pain and delirium in hospitalized older patients: a systematic review.

Peiman Prandeh Afshar, Eied Saber Alamain Ali, Fatemeh Dehghan, Mahlagha Dehghan

Abstract readSystematic Review
In one paragraph

Synthesis in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peiman Prandeh AfsharStudent Research Committee, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.ORCID http://orcid.org/0000-0002-6043-9387
Eied Saber Alamain AliCharge Nurse, Naufar Center, Doha, Qatar.ORCID http://orcid.org/0009-0006-2906-0973
Fatemeh DehghanArad Radman Brain Storming Co.LLC., Kerman, Iran.ORCID http://orcid.org/0009-0009-6348-0180
Mahlagha DehghanReproductive and Family Health Research Center, Kerman University of Medical Sciences, Kerman, Iran. m_dehghan86@yahoo.com.ORCID http://orcid.org/0000-0002-4205-829X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelirium and acute pain are common and serious problems in hospitalized older patients, often leading to adverse outcomes such as prolonged hospital stays, cognitive decline, and higher mortality rates. While pharmacological treatments can have significant side effects in older adults, non-pharmacological interventions offer safer alternatives.

objectiveThis systematic review aimed to evaluate the effectiveness of non-pharmacological interventions in managing acute pain and delirium in hospitalized older patients.

methodsA comprehensive search was conducted across PubMed, Scopus, Web of Science, Embase, Cochrane Library, and Google Scholar databases up to July 2025. The review included randomized controlled trials and quasi-experimental studies involving patients aged ≥ 65 years that used non-pharmacological interventions.

resultsThe review included eight studies. Music therapy and hand massage consistently reduced acute pain and anxiety among older patients, while the results for delirium prevention were mixed. some interventions, like geriatric care bundles, significantly reduced delirium incidence, while others showed no effect. These findings highlight the clinical relevance of non-pharmacological interventions as safer alternatives to pharmacological management in geriatric care.

conclusionNon-pharmacological interventions are effective in reducing acute pain and anxiety among older inpatients, with some showing promise in delirium prevention. However, the variability in intervention types and study quality highlights the need for standardized protocols and further research.

Indexed as

Acute PainDeliriumHospitalizationPain ManagementAgedAged, 80 and overHumansMassageMusic TherapyRandomized Controlled Trials as TopicDeliriumInterventionNon-pharmacologicalOlder patientsPain

Identifiers

PMID41444505
PMCPMC12729572

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.