Evidence map›Paper›PMID 41444449›Full record

ArticleTechniques in coloproctology2025

Role of transanal tube placement in preventing anastomotic leakage in rectal cancer surgery with sufficient perfusion confirmed by indocyanine green fluorescence imaging.

Koichiro Okada, Gaku Ohira, Ryota Miura, Toru Tochigi, Tetsuro Maruyama, Atsushi Hirata, Michihiro Maruyama, Hisahiro Matsubara

Abstract readEvaluation Study
In one paragraph

Article in Techniques in coloproctology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Koichiro OkadaDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuuou-Ku, Chiba, 260-8670, Japan. kookada@chiba-u.jp.
Gaku OhiraDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuuou-Ku, Chiba, 260-8670, Japan.
Ryota MiuraDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuuou-Ku, Chiba, 260-8670, Japan.
Toru TochigiDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuuou-Ku, Chiba, 260-8670, Japan.
Tetsuro MaruyamaDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuuou-Ku, Chiba, 260-8670, Japan.
Atsushi HirataDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuuou-Ku, Chiba, 260-8670, Japan.
Michihiro MaruyamaDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuuou-Ku, Chiba, 260-8670, Japan.
Hisahiro MatsubaraDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuuou-Ku, Chiba, 260-8670, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnastomotic leakage (AL) remains a major complication after rectal cancer surgery. Although various techniques have been proposed to reduce its incidence, the effectiveness of transanal tube (TA) placement remains controversial. This study aimed to evaluate whether combining indocyanine green (ICG) fluorescence angiography with TA placement reduces the risk of AL after rectal cancer surgery.

methodsA retrospective analysis, including patients who underwent rectal resection with primary anastomosis for rectal cancer, was performed. In all cases, anastomotic perfusion was assessed intraoperatively using ICG fluorescence angiography. Patients were categorized into two groups on the basis of postoperative TA placement: TA group and non-TA group. The primary outcome was the incidence of AL. Multivariate logistic regression and subgroup analyses based on tumor location were performed.

resultsThe TA group demonstrated a significantly lower incidence of AL compared with the control group (5% versus 18%, p = 0.02). Multivariate analysis identified male sex as a risk factor and TA placement as a protective factor for AL. Subgroup analysis revealed that TA placement was particularly effective in patients with middle rectal cancer.

conclusionsThe placement of a TA may offer additional benefit in reducing the risk of AL after rectal cancer surgery when adequate perfusion is confirmed using ICG fluorescence imaging, particularly in cases of middle rectal cancer.

Indexed as

Anastomotic LeakFluorescein AngiographyRectal NeoplasmsAgedAnal CanalAnastomosis, SurgicalColoring AgentsFemaleHumansIncidenceIndocyanine GreenMaleMiddle AgedOptical ImagingProctectomyRectumColoring AgentsIndocyanine GreenAnastomotic leakageAnastomotic perfusionIndocyanine green fluorescence angiographyRectal cancer surgeryTransanal tube

Identifiers

PMID41444449
PMCPMC12799619

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.