Evidence map›Paper›PMID 41444424›Full record

ArticleEuropean geriatric medicine2026

Individual and combined effects of somatic and mental disorders on reoperation risk after hip fracture surgery: a nationwide danish cohort study of 110,625 patients.

Simon Storgaard Jensen, Per Hviid Gundtoft, Jan-Erik Gjertsen, Alma Becic Pedersen

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Article in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Simon Storgaard JensenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark. ssj@clin.au.dk.ORCID http://orcid.org/0000-0002-7565-5656
Per Hviid GundtoftDepartment of Orthopaedic Surgery, Traumatology, Aarhus University Hospital, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-3688-6865
Jan-Erik GjertsenDepartment of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway.ORCID http://orcid.org/0000-0002-8490-268X
Alma Becic PedersenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-3288-9401

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurgical complications after hip fracture surgery are common, particularly among patients with comorbidities. We examined the risk of reoperation concerning individual comorbidity groups, their combinations, and overall comorbidity burden.

methodsUsing nationwide Danish registry data, we identified all patients undergoing hip fracture surgery between 2004 and 2021. Comorbidities were analysed as: (1) 10 major comorbidity groups, (2) all pairwise combinations of the 10 groups, and (3) overall comorbidity burden based on the 10 groups. Reoperation risk was estimated with 95% confidence intervals (CI), treating death as a competing event.

resultsWe included 110,625 patients, with a mean age of 82.4 years (70% female). The most prevalent comorbidity groups were cardiovascular (54%), renal/haematological (24%), and metabolic (20%) disorders. The highest 30-day reoperation risks were observed in patients with mental disorders 4.8% (CI 4.3-5.3) and musculoskeletal disorders 4.7% (CI 4.2-5.3). Compared with patients without comorbidities, adjusted hazard ratios (aHRs) for reoperation were 1.53 (CI 1.27-1.83) for neurological/alcohol disorders and 1.40 (CI 1.15-1.70) for mental disorders. Several combinations were associated with a significantly increased reoperation risk, highest for mental and hepatic/gastrointestinal disorders, with an aHR of 2.27 (CI 1.20-4.32). The reoperation risk increased with comorbidity burden, reaching an aHR of 1.33 (CI 1.11-1.59) for patients with ≥ 5 comorbidities. Similar patterns were seen at 365 days.

conclusionSpecific comorbidities, particularly mental, hepatic/gastrointestinal, neurological/alcohol, and musculoskeletal disorders, were associated with increased reoperation risk after hip fracture surgery. Risk was highest for certain comorbidity combinations, highlighting the prognostic value of comorbidity profiles beyond overall burden and supporting their use in stratified care.

Indexed as

Hip FracturesMental DisordersPostoperative ComplicationsReoperationAgedAged, 80 and overCohort StudiesComorbidityDenmarkFemaleHumansMaleRegistriesRisk FactorsComorbidityHip FractureInterdisciplinary treatmentMultimorbidityReoperation

Identifiers

PMID41444424

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