ArticleScientific reports2025
Phytochemical investigation and antibacterial activities of Cordia africana roots extracts.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Cordia africana is one of the traditional medicinal plants that is used for the treatment of malaria, liver diseases, stomachaches, and diarrhea. Despite its ethnomedicinal application, the phytochemical composition of its root and its antibacterial activities have not been reported. Therefore, the aim of this study was to investigate the phytochemicals of C. africana root and evaluate its antibacterial activity. The air-dried root of C .africana was sequentially extracted by dichloromethane and methanol (1:1 v/v), and methanol. Phytochemical screening of crude extracts showed the presence of flavonoids, steroids, triterpenoids, phenols, and tannins, while alkaloids were absent. The column chromatographic isolation of the dichloromethane: methanol (1:1 v/v) crude extracts yielded two compounds, compound-GT1 (trilinolein) and compound-GT2 (β-sitosterol). The structure elucidation of the isolated compounds was performed based on data from
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