ArticleInternal medicine (Tokyo, Japan)2026
Improvement of Lymphedema in IgG4-Related Disease with Oral Glucocorticoid Therapy.
Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Relapse in adult idiopathic inflammatory myopathies: clinical predictors and the potential role of anti-NXP2 in a single-center retrospective cohort study.Clinical rheumatology · 2026Article
- Concurrent anti-neutrophil cytoplasmic antibody-associated nephritis and IgG4-related tubulointerstitial nephritis: a rare case.Clinical rheumatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An 81-year-old Japanese man with IgG4-related disease (IgG4-RD) presented with marked edema in the right lower leg. He was diagnosed with IgG4-RD with retroperitoneal fibrosis, hilar and mediastinal lymphadenopathy, elevated serum IgG4 levels, and IgG4-positive plasma cell infiltration in a mediastinal lymph node. Lymphatic scintigraphy revealed an obstruction corresponding to edema due to retroperitoneal fibrosis. Glucocorticoid therapy resulted in rapid improvement. Lymphedema due to IgG4-RD with retroperitoneal fibrosis is rare and no standard treatment exists. This case underscores the importance of considering IgG4-RD which is a potentially reversible cause of lymphedema.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.