Evidence map›Paper›PMID 41443672›Full record

ArticleJournal of the science of food and agriculture2026

Probiotic fermentation of soybeans and use of fermented soy in cookies.

Xin Chen, Zhenjia Chen, Perry K W Ng, Yan Liu

Abstract read
In one paragraph

Article in Journal of the science of food and agriculture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xin ChenDepartment of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, MI, USA.
Zhenjia ChenDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA.
Perry K W NgDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA.
Yan LiuDepartment of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, MI, USA.ORCID https://orcid.org/0000-0002-5039-6731

Funding

The Michigan Soybean Committee
6 · The paper itself

Abstract

backgroundWith increasing prevalence of mental health issues such as insomnia and anxiety, γ-aminobutyric acid (GABA) has gained attention for its neurological benefits. The development of GABA-rich functional foods has emerged as a promising research direction. Soybeans, rich in glutamate, are excellent substrates for GABA biosynthesis using microbial fermentation. In this study, Lactococcus lactis (LL) and Lactiplantibacillus plantarum (LP) were used to ferment soybeans, aiming to enhance GABA production. The effects of fermentation on pH value, yield, colony-forming unit, phytic acid content, total phenol content, and ABTS

resultsCo-fermentation with LL and LP significantly reduced phytic acid levels. Mono-fermentation with LL showed higher probiotic viability, better retention of total phenolics and antioxidant capacity, and superior GABA accumulation. Cookies supplemented with LL-fermented soybean flour better maintained the hardness and exhibited a higher GABA content compared to those prepared with unfermented soybean flour (P < 0.05).

conclusionFermentation with LL effectively enhanced GABA content (P < 0.05) and preserved cookie texture comparable to that of 100% wheat flour cookies. These results can support the potential of LL fermentation in developing GABA-enriched plant-based functional foods. © 2025 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

Glycine maxLactiplantibacillus plantarumLactococcus lactisProbioticsAntioxidantsFermentationFermented FoodsFlourgamma-Aminobutyric AcidPhytic AcidAntioxidantsgamma-Aminobutyric AcidPhytic AcidcookiesfermentationLactiplantibacillus plantarumLactococcus lactisprobioticssoybean

Identifiers

PMID41443672
PMCPMC12967717

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.