Evidence map›Paper›PMID 41443267›Full record

ArticleChemMedChem2026

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications.

Antonio A de Oliveira-Neto, Gustavo Clauss, Jennyfer Castro, Marcus S A Garcia, Natasha M Cassani, Bruna C Sandim, Ana Laura C Oliveira, Stephanie P B Reyes, Nádija N P da Silva, Fillipe V Rocha and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemMedChem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Antonio A de Oliveira-NetoInstitute of Chemistry, University of Campinas, Campinas, 13083-970, São Paulo, Brazil.
Gustavo ClaussInstitute of Chemistry, University of Campinas, Campinas, 13083-970, São Paulo, Brazil.
Jennyfer CastroInstitute of Chemistry, University of Campinas, Campinas, 13083-970, São Paulo, Brazil.
Marcus S A GarciaInstitute of Biology, University of Campinas, Rua Monteiro Lobato, 255, Campinas, 13083-970, São Paulo, Brazil.
Natasha M CassaniLaboratory of Antiviral Research (LAPAV), Institute of Biomedical Sciences, Federal University of Uberlândia, João naves de Ávila Avenue, 2121, Uberlândia, 38408-100, Minas Gerais, Brazil.
Bruna C SandimLaboratory of Antiviral Research (LAPAV), Institute of Biomedical Sciences, Federal University of Uberlândia, João naves de Ávila Avenue, 2121, Uberlândia, 38408-100, Minas Gerais, Brazil.
Ana Laura C OliveiraLaboratory of Antiviral Research (LAPAV), Institute of Biomedical Sciences, Federal University of Uberlândia, João naves de Ávila Avenue, 2121, Uberlândia, 38408-100, Minas Gerais, Brazil.
Stephanie P B ReyesLaboratory of Antiviral Research (LAPAV), Institute of Biomedical Sciences, Federal University of Uberlândia, João naves de Ávila Avenue, 2121, Uberlândia, 38408-100, Minas Gerais, Brazil.
Nádija N P da SilvaDepartment of Chemistry, Federal University of São Carlos, Rodovia Washington Luis, São Carlos, 13565-905, São Paulo, Brazil.
Fillipe V RochaDepartment of Chemistry, Federal University of São Carlos, Rodovia Washington Luis, São Carlos, 13565-905, São Paulo, Brazil.
Ana C G JardimLaboratory of Antiviral Research (LAPAV), Institute of Biomedical Sciences, Federal University of Uberlândia, João naves de Ávila Avenue, 2121, Uberlândia, 38408-100, Minas Gerais, Brazil.
Danilo C MiguelInstitute of Biology, University of Campinas, Rua Monteiro Lobato, 255, Campinas, 13083-970, São Paulo, Brazil.
Camilla AbbehausenInstitute of Chemistry, University of Campinas, Campinas, 13083-970, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-8410-2252

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 140502/2024-6Conselho Nacional de Desenvolvimento Científico e Tecnológico 141021/2022-5Conselho Nacional de Desenvolvimento Científico e Tecnológico 304587/2022-2Conselho Nacional de Desenvolvimento Científico e Tecnológico 403429/2022-6Conselho Nacional de Desenvolvimento Científico e Tecnológico 404668/2021-6Conselho Nacional de Desenvolvimento Científico e Tecnológico 409187/2023-2Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) 88881.506794/2020-01Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) 88887.713008/2022-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Finance Code 001FAPEMIG Minas Gerais Research Foundation APQ-01487-22FAPEMIG Minas Gerais Research Foundation APQ-04686-22Financiadora de Estudos e Projetos (FINEP) 01.22.0182Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/02618-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/02876-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/12657-6
6 · The paper itself

Abstract

Complexes are emerging as promising alternatives for the treatment of neglected parasitic and viral infections, which urgently require new therapeutic strategies due to limited effective drugs. In this study, a series of [Pt(II)(phpy)(PR

Indexed as

Antineoplastic AgentsAntiprotozoal AgentsAntiviral AgentsCoordination ComplexesOrganoplatinum CompoundsPhosphinesAnimalsCell Line, TumorCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMolecular StructureParasitic Sensitivity TestsStructure-Activity RelationshipAntineoplastic AgentsAntiprotozoal AgentsAntiviral AgentsCoordination ComplexesOrganoplatinum CompoundsphosphinePhosphinesantileishmanialantiviralsneglected diseasesorganometallic platinum complexesphosphines

Identifiers

PMID41443267
PMCPMC12913238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.