Evidence map›Paper›PMID 41442601›Full record

ArticleBiomacromolecules2026

Encapsulated Control: Shaping Insulin Fibrillation through Polymer Confinement.

Anastasiia Murmiliuk, Sergey K Filippov, Hiroki Iwase, Kuno Schwärzer, Jürgen Allgaier, Aurel Radulescu

Abstract read
In one paragraph

Article in Biomacromolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anastasiia MurmiliukDepartment of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Segrate 20054, Italy.ORCID 0000-0001-6775-2563
Sergey K FilippovDWI - Leibniz Institute for Interactive Materials, Aachen 52074, Germany.ORCID 0000-0002-4253-5076
Hiroki IwaseNeutron Science and Technology Center, Comprehensive Research Organization for Science and Society (CROSS), Tokai, Ibaraki 319-1106, Japan.ORCID 0000-0003-4038-7839
Kuno SchwärzerJülich Centre for Neutron Science (JCNS-1), Forschungszentrum Jülich, Jülich 52425, Germany.ORCID 0009-0001-9936-9056
Jürgen AllgaierJülich Centre for Neutron Science (JCNS-1), Forschungszentrum Jülich, Jülich 52425, Germany.ORCID 0000-0002-9276-597X
Aurel RadulescuJülich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ), Forschungszentrum Jülich GmbH, Garching 85747, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The understanding of insulin conformational changes trapped inside a polymeric capsule is obscure, especially at elevated temperatures above 40 °C. We studied the conformational changes of insulin in bulk solution and upon encapsulation into polymeric self-assemblies formed by poly(ethylene oxide)-

Indexed as

InsulinNanoparticlesPolyethylene GlycolsPolymersHydrogen-Ion ConcentrationMethacrylatesTemperatureInsulinMethacrylatesPolyethylene GlycolsPolymers

Identifiers

PMID41442601
PMCPMC12801316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.