Evidence map›Paper›PMID 41441907›Full record

SynthesisJournal of neuro-oncology2025

Systematic review of disease-specific quality of life in patients with sporadic vestibular schwannoma.

Karl R Khandalavala, Nader G Zalaquett, Christine M Lohse, Michael J Link, Matthew L Carlson

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of neuro-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karl R Khandalavala *Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.
Nader G Zalaquett *Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.
Christine M LohseDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Michael J LinkDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.
Matthew L CarlsonDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA. carlson.matthew@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo systematically review the existent data on disease-specific quality of life (QOL) measures for sporadic vestibular schwannoma (VS), with a specific focus on comparing QOL outcomes among observation, radiosurgery, and microsurgery.

methodsSystematic review.

resultsA systematic review identified 751 unique publications on QOL in VS, with a total of 39 articles reporting disease-specific measures of QOL. Of these, 26 articles evaluated QOL of VS patients after management, including 14 that compared QOL metrics among observation, radiosurgery, and microsurgery. When comparing these three primary treatment modalities for VS, nine of the 14 articles did not demonstrate clinically significant differences in QOL scores among treatment types. There were no consistent trends among the publications to help guide selection of treatment modality based on QOL scores.

conclusionWhile disease-specific tools exist for quantifying QOL in VS, to date, no consistent, clinically significant differences in QOL have been reported among management strategies for patients with sporadic VS.

Indexed as

Neuroma, AcousticQuality of LifeHumansMicrosurgeryRadiosurgeryQuality of lifeVestibular schwannoma

Identifiers

PMID41441907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.