ArticleChemistry (Weinheim an der Bergstrasse, Germany)2026
Fluorescent Diarylethenes With Polar Groups: Synthesis, Spectra, and Optical Microscopy Applications.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of photoactivatable fluorescent diarylethenes (fDAEs) in biology-related light microscopy has been restricted by the lack of probes having freely variable structural and spectral properties. Facing these challenges, we synthesized "turn-on" fDAEs with four hydroxyl groups and a single functionality in the core structure (HO-fDAEs). HO-fDAEs emit green light; they were used for the preparation of cell-permeant mitochondrion-selective probes and bioconjugation with proteins (via a single COOH group). HO-fDAEs were combined in bio-imaging with a thiophene-substituted fDAE (Th-fDAE) possessing red-shifted absorption and emission bands of the open- and closed-ring isomers. Th-fDAE undergoes full on-switching with 405 nm and excitation with green light (< 560 nm). The large Stokes shifts of HO-and Th-fDAE (80 and 110 nm, respectively) and different excitation wavelengths permitted color separation in optical microscopy. Photoactivation of HO-fDAEs and transient on-off switching (blinking) of Th-fDAE made it possible to acquire two-color images of cellular structures with optical superresolution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.