Evidence map›Paper›PMID 41441707›Full record

ArticleVaccines2025

Geographical Patterns of COVID-19 Vaccine Inequality by Race and Ethnicity and Sociodemographic Determinants of Health: Evidence from Louisville, Kentucky.

Seyed M Karimi, Amir Hossein Hassani, Hamid Zarei, Mana Moghadami, Md Yasin Ali Parh, Shaminul H Shakib, Venetia Aranha, Mohammad Mansouri, Trey Allen, Yuting Chen and 5 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Seyed M KarimiDepartment of Health Management and Systems Sciences, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0002-3796-8141
Amir Hossein HassaniSchool of Medicine, Shiraz University of Medical Sciences, Shiraz 71348-51156, Iran.
Hamid ZareiDepartment of Health Management and Systems Sciences, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40292, USA.
Mana MoghadamiDepartment of Health Management and Systems Sciences, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40292, USA.
Md Yasin Ali ParhDepartment of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
Shaminul H ShakibDepartment of Public Health, College of Health Sciences, Sam Houston State University, Huntsville, TX 77340, USA.ORCID 0009-0001-8268-5984
Venetia AranhaDepartment of Epidemiology and Population Health, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0002-5913-6207
Mohammad MansouriDepartment of Economics (DSE), Alma Mater Studiorum Università di Bologna, 40126 Bologna, Italy.
Trey AllenDivision of Population Health, Louisville Metro Department of Public Health and Wellness, Louisville, KY 40202, USA.
Yuting ChenDivision of Population Health, Louisville Metro Department of Public Health and Wellness, Louisville, KY 40202, USA.
Sirajum Munira KhanDepartment of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40292, USA.
Farzaneh RaoofiDepartment of Mathematics, College of Arts & Sciences, University of Louisville, Louisville, KY 40292, USA.
Sepideh PoursafargholiDepartment of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40292, USA.
Taylor IngramDown Syndrome of Louisville, Louisville, KY 40204, USA.
Angela GrahamDivision of Population Health, Louisville Metro Department of Public Health and Wellness, Louisville, KY 40202, USA.

Funding

Louisville Metro Department of Public Health and Wellness (LMPHW) OGMB220965B
6 · The paper itself

Abstract

backgroundInfectious diseases accounted for approximately 18.4% of global mortality in 2019. According to the World Health Organization (WHO), vaccines are available for about 30 potentially lethal diseases. Vaccination prevents substantial mortality and hospitalization. However, its ability to improve overall public health depends on equitable access across all populations, regardless of race, ethnicity, education, or socioeconomic status.

objectivesThis study aims to examine how disparities in social determinants of health (SDOH) affect COVID-19 vaccination uptake across Jefferson County, Kentucky. Using ZIP code-level spatial mapping, this study investigates the intersection of SDOH, racial composition, and geographic characteristics to identify inequities and inform equitable interventions.

methodsData from the Kentucky Immunization Registry (KYIR) were analyzed to assess two-dose COVID-19 vaccination rates at the ZIP code and regional levels in Jefferson County, Kentucky. Vaccination rates were stratified by race and ethnicity and linked with SDOH, including education, employment, insurance status, and income, obtained from the 2021 American Community Survey.

resultsBy May 2021, vaccination rates ranged from 25.9% in the West region to 57.0% in the Inner East region; by May 2022, these rates increased to 46.2% and 73.9%, respectively. White residents consistently had the highest two-dose vaccination rates (66.4% by May 2022), while Black and Hispanic residents had lower rates (45.7% and 43.9%, respectively). Vaccination rates were strongly correlated with SDOH, especially educational attainment, average family income, and employment rate, underscoring the role of socioeconomic inequities in vaccination disparities.

conclusionsGeographical and racial disparities emphasize the influence of social and economic inequality on vaccine uptake.

Indexed as

COVID-19 vaccinationJefferson CountyKentuckyracial and ethnic disparitiessocial determinants of healthspatial analysisvaccine equity

Identifiers

PMID41441707
PMCPMC12737567

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.