Evidence map›Paper›PMID 41441696›Full record

ArticleVaccines2025

Colloidal Manganese Salt Improves the Efficacy of

Chebing Huang, Shaoyuan Bai, Haiqiong Yu, Ming Pan, Zhaofeng Hou, Lizhi Fu, Siyang Huang

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Advances and Translational Challenges inVeterinary sciences · 2026
    Review
  2. Veterinary sciences · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chebing HuangInstitute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, and Jiangsu Key Laboratory of Zoonosis, Yangzhou 225009, China.
Shaoyuan BaiInstitute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, and Jiangsu Key Laboratory of Zoonosis, Yangzhou 225009, China.ORCID 0009-0000-5086-8375
Haiqiong YuGuangzhou Customs District Technology Center, Guangzhou 510623, China.
Ming PanInstitute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, and Jiangsu Key Laboratory of Zoonosis, Yangzhou 225009, China.
Zhaofeng HouInstitute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, and Jiangsu Key Laboratory of Zoonosis, Yangzhou 225009, China.ORCID 0000-0003-3680-6156
Lizhi FuChongqing Academy of Animal Sciences, Chongqing 402460, China.
Siyang HuangInstitute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, and Jiangsu Key Laboratory of Zoonosis, Yangzhou 225009, China.ORCID 0000-0003-1452-1299

Funding

Si-Yang Huang 24535CSi-Yang Huang NCTIP-XD/B19
6 · The paper itself

Abstract

BACKGROUND/

objectivesToxoplasmosis caused by

methodsIn this study, we combined the inactivated

resultsThis triggered a powerful innate immunity, significantly increased the number of CD4

conclusionsThese results suggested that the incorporation of an MnJ adjuvant significantly enhances the immunoprotective efficacy of inactivated

Indexed as

adjuvantcolloidal manganese saltimmune responseToxoplasma gondiivaccine

Identifiers

PMID41441696
PMCPMC12737533

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.