Evidence map›Paper›PMID 41441650›Full record

ReviewVaccines2025

Self-Assembled Peptides: A New Generation of Vaccine Adjuvant Platform.

Miao-Miao Zhang, Ji Zhu, Zhao-Yi Wang, Yu-Lun Bai, Hai-Bo Li, Buhe Nashun, Yue Jiang

Abstract readReview
In one paragraph

Review in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miao-Miao ZhangInner Mongolia Key Laboratory for Molecular Regulation of the Cell, School of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Ji ZhuNational Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Zhao-Yi WangNational Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Yu-Lun BaiNational Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Hai-Bo LiNational Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University (Army Medical University), Chongqing 400038, China.ORCID 0000-0003-4014-3770
Buhe NashunInner Mongolia Key Laboratory for Molecular Regulation of the Cell, School of Life Sciences, Inner Mongolia University, Hohhot 010070, China.
Yue JiangNational Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University (Army Medical University), Chongqing 400038, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advent of precision medicine has spotlighted subunit and peptide-based vaccines, which offer high safety but often require potent adjuvants to enhance immunogenicity. Self-assembled peptides have emerged as a promising adjuvant platform due to their ease of synthesis, excellent biocompatibility, and tunable structural properties. Recent advances highlight their potential in boosting vaccine efficacy, with self-assembled peptides forming highly ordered architectures that are conducive to immune system activation. This review discusses the key factors driving peptide self-assembly and explores their evolving role as innovative vaccine adjuvants, alongside challenges and future development directions.

Indexed as

adjuvantsnanostructuresself-assembly peptidesvaccines

Identifiers

PMID41441650
PMCPMC12737621

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.