Evidence map›Paper›PMID 41441632›Full record

Observational studyToxins2025

Artificial Intelligence Analysis of Symmetry and Emotions in Facial Palsy Patients After Botulinum Toxin A Injections.

Seraina L C Müller, Chantal Zeier, Pablo Pfister, Nadia Menzi, Bita Tafrishi, Dirk J Schaefer, Jan A Plock, Tarek Ismail, Holger J Klein

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seraina L C MüllerDepartment of Plastic, Reconstructive, Aesthetic, and Hand Surgery, University Hospital Basel, 4031 Basel, Switzerland.ORCID 0009-0003-5531-1316
Chantal ZeierMedical University of Zurich, 8006 Zurich, Switzerland.
Pablo PfisterDepartment of Plastic, Reconstructive, Aesthetic, and Hand Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Nadia MenziDepartment of Plastic, Reconstructive, Aesthetic, and Hand Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Bita TafrishiDepartment of Plastic Surgery and Hand Surgery, Cantonal Hospital Aarau, 5001 Aarau, Switzerland.
Dirk J SchaeferDepartment of Plastic, Reconstructive, Aesthetic, and Hand Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Jan A PlockDepartment of Plastic Surgery and Hand Surgery, Cantonal Hospital Aarau, 5001 Aarau, Switzerland.
Tarek IsmailDepartment of Plastic, Reconstructive, Aesthetic, and Hand Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Holger J KleinDepartment of Plastic Surgery and Hand Surgery, Cantonal Hospital Aarau, 5001 Aarau, Switzerland.

Funding

Gottfried & Julia Bangerter-Rhyner-Stiftung on my Name: Seraina Müller
6 · The paper itself

Abstract

Facial palsy affects millions worldwide. Botulinum toxin Type A (BoNT-A) is an established treatment for non-flaccid facial palsy, yet objective evidence remains limited. This study evaluates the effects of BoNT-A using AI-based tools and patient-reported outcome measures (PROMs). In this prospective observational study, patients with non-flaccid facial palsy received individualized BoNT-A injections. Exclusion criteria included age < 18, hypersensitivity to BoNT-A, or lack of follow-up. Assessments were conducted before and 3 weeks after treatment, including facial symmetry (Emotrics

Indexed as

Artificial IntelligenceBotulinum Toxins, Type AEmotionsFacial ParalysisNeuromuscular AgentsAdultAgedFacial ExpressionFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresPatient SatisfactionProspective StudiesTreatment OutcomeBotulinum Toxins, Type ANeuromuscular Agentsartificial intelligenceBotulinum toxinfacial palsyPROMs

Identifiers

PMID41441632
PMCPMC12737524

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.