Evidence map›Paper›PMID 41441619›Full record

ArticleToxins2025

Beta Toxins Isolated from the Scorpion

Laura L Valdez-Velazquez, Timoteo Olamendi-Portugal, Rita Restano-Cassulini, Lidia Riaño-Umbarila, Juana María Jiménez-Vargas, Fernando Zamudio, Hermenegildo Salazar-Monge, Baltazar Becerril, Lourival D Possani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura L Valdez-VelazquezFacultad de Ciencias Químicas y Facultad de Medicina, Universidad de Colima, Km 9 Carretera Colima, Coquimatlán s/n, Coquimatlán 28400, Mexico.ORCID 0000-0001-8474-1495
Timoteo Olamendi-PortugalDepartamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, Mexico.ORCID 0000-0002-3220-6906
Rita Restano-CassuliniDepartamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, Mexico.ORCID 0000-0001-6510-5303
Lidia Riaño-UmbarilaDepartamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, Mexico.ORCID 0000-0002-2531-9232
Juana María Jiménez-VargasFacultad de Ciencias Químicas y Facultad de Medicina, Universidad de Colima, Km 9 Carretera Colima, Coquimatlán s/n, Coquimatlán 28400, Mexico.ORCID 0000-0001-9508-9332
Fernando ZamudioDepartamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, Mexico.
Hermenegildo Salazar-MongeFacultad de Medicina, Universidad de Colima, Avenida Universidad 333, las Víboras, Colima 28040, Mexico.ORCID 0000-0001-6613-0877
Baltazar BecerrilDepartamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, Mexico.
Lourival D PossaniDepartamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, Mexico.ORCID 0000-0001-6357-2661

Funding

CONAHCYT PRONACE 303045DGAPA-UNAM IN200323Universidad de Colima Fortalecimiento de la investigación 2023 grant
6 · The paper itself

Abstract

Scorpion venom toxins are important peptides being studied for their clinical significance. These peptides act by binding to ion channels in the membrane of nerve cells, causing the symptoms associated with scorpion stings (scorpionism). They principally affect the function of voltage-gated sodium channels (Nav) and are valuable for studying ion channels. Scorpions from the Buthidae family contain toxins that affect sodium channels and have a high affinity for mammalian channels. In this study, two sodium toxins isolated from the venom of the scorpion

Indexed as

ScorpionsScorpion VenomsSodium ChannelsAmino Acid SequenceAnimalsAnimals, PoisonousHumansVoltage-Gated Sodium ChannelsScorpion VenomsSodium ChannelsVoltage-Gated Sodium ChannelsCentruroides hirsutipalpusscorpionvoltage-gated sodium channelsβ-toxins

Identifiers

PMID41441619
PMCPMC12737490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.